DIHYDROERGOTAMINE CAS#: 511-12-6

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DIHYDROERGOTAMINE

Basic information Safety Supplier Related

DIHYDROERGOTAMINE Basic information

Product Name:

DIHYDROERGOTAMINE

Synonyms:

Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-
DIHYDROERGOTAMINE
Dihydroergotamine (base and/or unspecified salts)
9,10-Dihydroergotamine
9,10α-Dihydro-12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione
Levadex
DIHYDROERGOTAMINE USP/EP/BP
Dihydro Ergotamine D5

CAS:

511-12-6

MF:

C33H37N5O5

MW:

583.69

EINECS:

208-123-3

Mol File:

511-12-6.mol

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DIHYDROERGOTAMINE Chemical Properties

Melting point:: 239°
alpha: D20 -64°; 20546 -79° (c = 0.5 in pyridine)
Boiling point:: 641.14°C (rough estimate)
Density: 1.1992 (rough estimate)
refractive index: 1.7500 (estimate)
pka: 9≅+-.0.60(Predicted)

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DIHYDROERGOTAMINE Usage And Synthesis

Uses

Anti-adrenergic.

Uses

Levadex is an intermediate in the synthesis of 2’-Epidihydroergotamine (E584910), which is an ergot alkaloid that exhibits potential neuroprotective properties against degenerative diseases.

Definition

ChEBI: Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the tr atment of migraine and orthostatic hypotension.