Peimine Chemical Properties

Melting point:

223-224°

alpha 

D16 -19.4° (ethanol); D17 -20° (CHCl3)

Boiling point:

568.4±50.0 °C(Predicted)

Density 

1.18±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

Acetonitrile (Slightly, Heated, Sonicated), Chloroform (Slightly), Ethanol (Slightly)

pka

9.5(at 25℃)

form 

Solid

color 

White to Off-White

Safety Information

Safety Statements 

24/25

HS Code 

29420000

Peimine Usage And Synthesis

Description

Fritillaria verticillata var. Thunbergii also yields this steroidal alkaloid which was originally given the formulae ClsH3302N or C19H3S02N. The base has [α]¹⁰_D -10.66° (EtOH), yields a crystalline perchlorate, a platinichloride, and contains three non-phenolic hydroxyl groups. The nitrogen atom is tertiary in character. Chi and his colleagues regard the alkaloid as identical with Peimine (q.v.).

Chemical Properties

White crystals, soluble in chloroform, derived from Fritillaria thunbergii.

Uses

Peimine is a steroidal alkaloid compound extracted from the Fritillaria species of medicinal plants.

Definition

ChEBI: Verticine is an alkaloid.

References

Fukuda., Sci. Rep. Tohoku Imp. Univ., 18,323 (1929) Chi, Kao, Chang.,i. Amer. Chern. Soc., 58, 1306 (1936) Chi, Kao, Chang., ibid, 62, 1778 (1944)

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