FUMITREMORGIN C
FUMITREMORGIN C Basic information
- Product Name:
- FUMITREMORGIN C
- Synonyms:
-
- Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem
- FuMitreMorgin CFuMitreMorg
- (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione
- 12alpha-Fumitremorgin C
- 5H,14H-Pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione,1,2,3,5a,6,11,12,14a-octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-,(5aS,12S,14aS)-
- Fumitremorgin C, 98%, from Aspergillus fumigatus
- 12α-Fumitremorgin C
- Fumitremorgin C, from Aspergillus fumigatus
- CAS:
- 118974-02-0
- MF:
- C22H25N3O3
- MW:
- 379.45
- Mol File:
- 118974-02-0.mol
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FUMITREMORGIN C Chemical Properties
- Melting point:
- 259.5-260.5℃
- Boiling point:
- 642.9±55.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- acetonitrile: 5 mg/mL, soluble
- form
- solid
- pka
- 17.16±0.40(Predicted)
- color
- White to light brown
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 2941900000
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FUMITREMORGIN C Usage And Synthesis
Uses
Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.
Definition
ChEBI: An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.
General Description
A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug transport activity. Also acts as a potent and specific chemosenzitizing agent.
Biochem/physiol Actions
Cell permeable: yes
target
Antifection | P-gp
storage
+4°C
FUMITREMORGIN CSupplier
Nanjing Shizhou Biology Technology Co.,Ltd Gold
- Tel
- 025-85560043 13675144456
- sean.lv@synzest.com
BioBioPha Co., Ltd.
- Tel
- 0871-65217109 13211707573;
- y.liu@mail.biobiopha.com
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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- 18521735133 18521732826;
- market@aladdin-e.com
MedChemexpress LLC
- Tel
- 021-58955995
- sales@medchemexpress.cn
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com
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