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ANHYDROERYTHROMYCIN A

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ANHYDROERYTHROMYCIN A Basic information

Product Name:
ANHYDROERYTHROMYCIN A
Synonyms:
  • Erythromycin EP Impurity D/Anhydroerythromycin A/(1S,2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-9- [(2,6-dideoxy-3-C-methyl-3-O-methyl-α-Lribo-hexopyranosyl)oxy]-5-ethyl-3-hydroxy- 2,4,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3- (dimethylamino)-β-D-xylo-hexopyra
  • 6,9,12-Anhydroerythromycin A
  • 9-Deoxo-6,12-dideoxy-6,9:9,12-diepoxy-erythromycin
  • Anhydroerythromycin
  • BRL 46355ER
  • EM 202
  • Erythromycin Anhydride, Impurity D
  • ANHYDROERYTHROMYCIN A
CAS:
23893-13-2
MF:
C37H65NO12
MW:
715.91
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
23893-13-2.mol
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ANHYDROERYTHROMYCIN A Chemical Properties

Melting point:
125-127°C
Boiling point:
787.2±60.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Chloroform (Slightly), Methanol (Sparingly)
pka
13.46±0.70(Predicted)
color 
White to Pale Yellow
EPA Substance Registry System
Erythromycin, 9-deoxo-6,12-dideoxy-6,9:9,12-diepoxy- (23893-13-2)
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Safety Information

WGK Germany 
3
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ANHYDROERYTHROMYCIN A Usage And Synthesis

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Anhydroerythromycin A is a degradation product of erythromycin formed by a complex internal rearrangement of erythromycin A on exposure to acidic conditions. In acid, erythromycin A forms the enol ether and then undergoes a second internal cyclisation of the C12–OH and C9 enol to afford the ketal, anhydroerythromycin A. Anhydroerythromycin A is an important analytical standard for erythromycin A stability studies.

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