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Levodropropizine

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Levodropropizine Basic information

Product Name:
Levodropropizine
Synonyms:
  • (S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
  • (2S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
  • Danka
  • l-Dropropizine
  • Levotuss
  • LVDP
  • Rapitux
  • Levodropropizine
CAS:
99291-25-5
MF:
C13H20N2O2
MW:
236.31
EINECS:
640-087-8
Product Categories:
  • raw materials
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • 99291-25-5
  • API
Mol File:
99291-25-5.mol
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Levodropropizine Chemical Properties

Melting point:
98-100°C
Boiling point:
412.7±34.0 °C(Predicted)
Density 
1.168±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Slightly soluble in water, freely soluble in dilute acetic acid and in methanol, slightly soluble in ethanol (96 per cent).
pka
14.21±0.20(Predicted)
color 
White to Almost white
InChI
InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2/t13-/m0/s1
InChIKey
PTVWPYVOOKLBCG-ZDUSSCGKSA-N
SMILES
C(O)[C@@H](O)CN1CCN(C2=CC=CC=C2)CC1
CAS DataBase Reference
99291-25-5(CAS DataBase Reference)
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Safety Information

HS Code 
2933.59.5300
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Levodropropizine Usage And Synthesis

Chemical Properties

White Solid

Uses

Cough Suppressant

Uses

S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive.

Definition

ChEBI: A member of the class of N-arylpiperazines that is N-phenylpiperazine in which the amino hydrogen is replaced by a 2,3-dihydroxypropyl group (the S-enantiomer). A peripherally acting antitussive drug t at is used as an alternative to opioids.

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