Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Piperazine compounds >  Levodropropizine

Levodropropizine

Basic information Safety Supplier Related

Levodropropizine Basic information

Product Name:
Levodropropizine
Synonyms:
  • (S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
  • (2S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
  • Danka
  • l-Dropropizine
  • Levotuss
  • LVDP
  • Rapitux
  • Levodropropizine
CAS:
99291-25-5
MF:
C13H20N2O2
MW:
236.31
EINECS:
640-087-8
Product Categories:
  • raw materials
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • 99291-25-5
  • API
Mol File:
99291-25-5.mol
More
Less

Levodropropizine Chemical Properties

Melting point:
98-100°C
Boiling point:
412.7±34.0 °C(Predicted)
Density 
1.168±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Slightly soluble in water, freely soluble in dilute acetic acid and in methanol, slightly soluble in ethanol (96 per cent).
pka
14.21±0.20(Predicted)
form 
Solid
color 
White to Almost white
Major Application
pharmaceutical (small molecule)
InChI
InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2/t13-/m0/s1
InChIKey
PTVWPYVOOKLBCG-ZDUSSCGKSA-N
SMILES
C(O)[C@@H](O)CN1CCN(C2=CC=CC=C2)CC1
CAS DataBase Reference
99291-25-5(CAS DataBase Reference)
More
Less

Safety Information

WGK Germany 
WGK 3
HS Code 
2933.59.5300
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
More
Less

Levodropropizine Usage And Synthesis

Chemical Properties

White Solid

Uses

Cough Suppressant

Uses

S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive.

Definition

ChEBI: A member of the class of N-arylpiperazines that is N-phenylpiperazine in which the amino hydrogen is replaced by a 2,3-dihydroxypropyl group (the S-enantiomer). A peripherally acting antitussive drug t at is used as an alternative to opioids.

Biological Activity

Levodropropizine has affinity for H1-histaminic and α-adrenergic receptors. Cough suppressant.

LevodropropizineSupplier

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Email
jkinfo@jkchemical.com
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Email
chenyj@titansci.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Email
info@yuhaochemical.com