ACETYLLOVASTATIN
ACETYLLOVASTATIN Basic information
- Product Name:
- ACETYLLOVASTATIN
- Synonyms:
-
- ACETYLLOVASTATIN
- Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-(acetyloxy)tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, (2S)-
- CAS:
- 81189-92-6
- MF:
- C26H38O6
- MW:
- 446.58
- Mol File:
- 81189-92-6.mol
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ACETYLLOVASTATIN Chemical Properties
- Boiling point:
- 568.9±50.0 °C(Predicted)
- Density
- 1.12±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 250 mg/mL (559.81 mM)
- form
- Solid
- color
- White to off-white
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ACETYLLOVASTATIN Usage And Synthesis
Uses
Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines[1].
References
[1] Cazar, et al. Antimicrobial Butyrolactone I Derivatives from the Ecuadorian Soil Fungus Aspergillus terreus Thorn. var terreus. World Journal of Microbiology and Biotechnology, 2005,21(6-7), 1067–1075.
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