ChemicalBook > Product Catalog > API > Nervous system drugs > Antipsychotics > HALOPERIDOL DECANOATE
HALOPERIDOL DECANOATE
HALOPERIDOL DECANOATE Basic information
- Product Name:
- HALOPERIDOL DECANOATE
- Synonyms:
-
- HALOPERIDOL DECANOATE
- MW:
- 0
- Mol File:
- Mol File
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HALOPERIDOL DECANOATE Chemical Properties
- Melting point:
- 42-44°C
- storage temp.
- Room Temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- color
- White
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HALOPERIDOL DECANOATE Usage And Synthesis
Uses
Antipsychotic.
brand name
Haldol (Ortho-McNeil).
General Description
Haloperidol decanoate, 4-[4-(4-chlorophenyl)-4-hydroxypiperidino]-4-fluorobutyrophenonedecanoate (Haldol Decanoate), is the decanoate ester(prodrug) of haloperidol. Peak plasma concentrations occurwithin 3 to 9 days and then decrease slowly. Haloperidol decanoatehas no intrinsic activity. Haloperidol decanoate undergoes hydrolysis by plasma and/or tissue esterases toform haloperidol and decanoic acid, subsequently; haloperidolis metabolized in the liver. The pharmacological effectsare those of haloperidol, which is released by bioconversion.Haloperidol decanoate is indicated for the treatment of longtermmaintenance in schizophrenia, psychoses especiallyparanoid, and other mental and behavioral problems.