DLK1 antibody Usage And Synthesis

Source

Rabbit

Reactivity

Human;Mouse

Background

Delta-like-1, also known as fetal antigen 1 and preadipocyte factor 1, is a member of the epidermal growth factor-like family of proteins, containing six tandem EGF-like repeats. DLK1 is a paternally expressed, imprinted gene that plays an important role in normal development and in the maintenance of homeostasis of adipose tissue mass. DLK1-deficient mice display growth retardation, obesity, skeletal malformation, and increased serum lipid metabolites. It has been reported that the ectodomain of DLK1 is shredded from the cell surface and inhibits adipocyte differentiation.

References

[1] Laborda, J. et al. (1993) J Biol Chem 268, 3817-20.
[2] Smas, C.M. and Sul, H.S. (1993) Cell 73, 725-34.
[3] Kobayashi, S. et al. (2000) Genes Cells 5, 1029-37.
[4] Moon, Y.S. et al. (2002) Mol Cell Biol 22, 5585-92.
[5] Smas, C.M. et al. (1997) Mol Cell Biol 17, 977-88.
[6] Mei, B. et al. (2002) Biochem J 364, 137-44.
[7] Wang, Y. et al. (2006) J Nutr 136, 2953-6.

DLK1 antibody()Related Product Information

• SELE Antibody
• RNF122 antibody
• AIF1 antibody
• LTB Antibody
• PGF antibody
• SNAI2 antibody
• SCR3
• IFI35 antibody
• BRSK2 ANTIBODY
• PIWI L1 antibody