9-AMINOACRIDINE Chemical Properties

Melting point:

238-240℃

Boiling point:

320.68°C (rough estimate)

Density 

1.268

refractive index 

1.5014 (estimate)

storage temp. 

Store below +30°C.

solubility 

ethanol: hazy

pka

9.99(at 20℃)

form 

Solid

color 

Yellow

Water Solubility 

11.65mg/L(24 ºC)

λmax

406nm(DMF)(lit.)

Merck 

14,407

Stability:

Stable. Incompatible with strong oxidizing agents.

InChIKey

XJGFWWJLMVZSIG-UHFFFAOYSA-N

CAS DataBase Reference

90-45-9(CAS DataBase Reference)

EPA Substance Registry System

9-Aminoacridine (90-45-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

2811

WGK Germany 

3

RTECS 

AR7300000

HS Code 

2933 99 80

HazardClass 

6.1(b)

PackingGroup 

III

Toxicity

LD50 intraperitoneal in mouse: 68mg/kg

MSDS

• Language:English Provider:SigmaAldrich

9-AMINOACRIDINE Usage And Synthesis

Chemical Properties

yellow crystals or powder

Uses

Acridine analog. DNA intercalating agent.

Uses

antibacterial

Uses

A MALDI matrix exhibiting low background and good sensitivity in the analysis of low molecular weight anions, such as metabolites, in negative mode

Definition

ChEBI: An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections

brand name

Monacrin (Sterling Winthrop).

General Description

Yellow needles. Free soluble in alcohol.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

9-AMINOACRIDINE is a moderately strong base. Neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

Flash point data for 9-AMINOACRIDINE are not available; however, 9-AMINOACRIDINE is probably combustible.

Purification Methods

It crystallises from EtOH or acetone and sublimes at 170-180o/0.04mm [Albert & Ritchie Org Synth Coll Vol III 53 1955, for hydrochloride, see below]. [Beilstein 22 H 463, 21 II 280, 21 III/IV 4174.]

9-AMINOACRIDINE(90-45-9)Related Product Information

• 9-AMINOACRIDINE HCL,9-AMINOACRIDINE HYDROCHLORIDE
• acrisorcin
• 9-AMINOACRIDINE
• QUINACRINE MUSTARD DIHYDROCHLORIDE
• 9-Aminoacridine hydrochloride hydrate
• Mepacrine hydrochloride
• Amsacrine
• 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
• 9-HYDRAZINOACRIDINE
• NAM
• Ethacridine lactate monohydrate
• 2-ETHOXY-6,9-DIAMINOACRIDINE
• 1,2,3,4-TETRAHYDRO-5-AMINOACRIDINE HYDROCHLORIDE
• 1,2,3,4-Tetrahydro-5-aminoacridine,1,2,3,4-Tetrahydro-9-aminoacridine
• 2-Methoxy-6-chloro-9-aminoacridine,3-Chloro-7-methoxy-9-aminoacridine
• 9-AMINOACRIDINE HEMIHYDRATE
• Luminol
• Acridine