Nicotinamide-N-oxide Chemical Properties

Melting point:

291-293 °C (dec.)(lit.)

Boiling point:

253.51°C (rough estimate)

Density 

1.3471 (rough estimate)

refractive index 

1.5100 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

DMSO (Slightly, Heated), Methanol (Slightly, Heated)

form 

Solid

pka

14.38±0.50(Predicted)

color 

White to Off-White

Sensitive 

Hygroscopic

CAS DataBase Reference

1986-81-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29339900

MSDS

• Language:English Provider:3-(Aminocarbonyl)pyridinium-1-olate
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

Nicotinamide-N-oxide Usage And Synthesis

Description

Nicotinamide N-oxide is a metabolite of nicotinamide . It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT; ), indicating cell differentiation, in HL-60 promyelocytic leukemia cells. Urine levels of nicotinamide N-oxide are elevated in a mouse model of high-fat diet-induced obesity.

Chemical Properties

WHITE TO SLIGHTLY YELLOW FLUFFY CRYST. NEEDLES

Uses

A metabolite of Nicotinamide.

Definition

ChEBI: Nicotinamide N-oxide is a member of pyridines.

Nicotinamide-N-oxide(1986-81-8)Related Product Information

• ETHYLENE OXIDE
• Nicotinamide
• NITRIC OXIDE
• Iron oxide
• Pyridinium chlorochromate
• Zinc oxide
• Magnesium oxide
• Propylene oxide
• THIONICOTINAMIDE
• (Diethoxymethyl)diphenylphosphine oxide
• Ethyl nicotinate
• Nicotinic acid
• NAD+
• Nicotinamide riboside
• MYRISTYL NICOTINATE
• Nicotinic Acid Riboside
• Benzyl nicotinate
• β-Nicotinamide Mononucleotide