ChemicalBook > Product Catalog > Biochemical Engineering > Nucleoside drugs > Nucleotides and their analogs > Nicotinamide-N-oxide
Nicotinamide-N-oxide
Nicotinamide-N-oxide Basic information
- Product Name:
- Nicotinamide-N-oxide
- Synonyms:
-
- 1-OXY-NICOTINAMIDE
- 3-(AMINOCARBONYL)PYRIDINIUM-1-OLATE
- AKOS 94294
- NICOTINAMIDE 1-OXIDE
- NICOTINAMIDE N-OXIDE
- TIMTEC-BB SBB004187
- 3-Pyridinecarboxamide, 1-oxide
- 3-Pyridinecarboxamide,1-oxide(9CI)
- CAS:
- 1986-81-8
- MF:
- C6H6N2O2
- MW:
- 138.12
- EINECS:
- 217-859-4
- Product Categories:
-
- Amines, Heterocycles, Metabolites & Impurities, Nicotine Derivatives, Nucleotides, Bases & Related Reagents
- Amines
- Bases & Related Reagents
- Heterocycles
- Metabolites & Impurities
- Nicotine Derivatives
- AMIDE
- Biochemicals and Reagents
- NAD and Analogs
- Nucleosides, Nucleotides, Oligonucleotides
- Nucleotides
- Mol File:
- 1986-81-8.mol
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Nicotinamide-N-oxide Chemical Properties
- Melting point:
- 291-293 °C (dec.)(lit.)
- Boiling point:
- 253.51°C (rough estimate)
- Density
- 1.3471 (rough estimate)
- refractive index
- 1.5100 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 14.38±0.50(Predicted)
- color
- White to Off-White
- Sensitive
- Hygroscopic
- CAS DataBase Reference
- 1986-81-8(CAS DataBase Reference)
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MSDS
- Language:English Provider:3-(Aminocarbonyl)pyridinium-1-olate
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
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Nicotinamide-N-oxide Usage And Synthesis
Description
Nicotinamide N-oxide is a metabolite of nicotinamide . It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT; ), indicating cell differentiation, in HL-60 promyelocytic leukemia cells. Urine levels of nicotinamide N-oxide are elevated in a mouse model of high-fat diet-induced obesity.
Chemical Properties
WHITE TO SLIGHTLY YELLOW FLUFFY CRYST. NEEDLES
Uses
A metabolite of Nicotinamide.
Definition
ChEBI: Nicotinamide N-oxide is a member of pyridines.
Nicotinamide-N-oxide Preparation Products And Raw materials
Preparation Products
Raw materials
Nicotinamide-N-oxideSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006608290; 18621169109
- market03@meryer.com
Alfa Aesar
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- 400-6106006
- saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
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- 021-67121386
- Sales-CN@TCIchemicals.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
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Nicotinamide-N-oxide(1986-81-8)Related Product Information
- ETHYLENE OXIDE
- Nicotinamide
- NITRIC OXIDE
- Iron oxide
- Pyridinium chlorochromate
- Zinc oxide
- Magnesium oxide
- Propylene oxide
- THIONICOTINAMIDE
- (Diethoxymethyl)diphenylphosphine oxide
- Ethyl nicotinate
- Nicotinic acid
- NAD+
- Nicotinamide riboside
- MYRISTYL NICOTINATE
- Nicotinic Acid Riboside
- Benzyl nicotinate
- β-Nicotinamide Mononucleotide