Sodium pyrophosphate Chemical Properties

Melting point:

decomposes 220℃ [MER06]

Density 

(hexahydrate) 1.86

vapor pressure 

0Pa at 20℃

storage temp. 

-70°C

solubility 

H₂O: 0.1 M at 20 °C, clear, colorless

form 

white powder

color 

White to Off-White

PH

3.5-4.5 (20℃, 0.1M in H2O, freshly prepared)

Water Solubility 

Fully miscible in water. Insoluble in alcohol and ammonia.

λmax

λ: 260 nm Amax: 0.11
λ: 280 nm Amax: 0.09

Merck 

13,8643

Stability:

Stable.

InChI

InChI=1S/Na.H4O7P2.H/c;1-8(2,3)7-9(4,5)6;/h;(H2,1,2,3)(H2,4,5,6);

InChIKey

IQTFITJCETVNCI-UHFFFAOYSA-N

SMILES

O(P(O)(O)=O)P(O)(O)=O.[NaH]

LogP

-3.420 (est)

CAS DataBase Reference

7758-16-9(CAS DataBase Reference)

EPA Substance Registry System

Disodium diphosphate (7758-16-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

24/25-26

WGK Germany 

2

RTECS 

UX6475000

TSCA 

Yes

Hazardous Substances Data

7758-16-9(Hazardous Substances Data)

MSDS

• Language:English Provider:Disodium pytophosphate
• Language:English Provider:SigmaAldrich

Sodium pyrophosphate Usage And Synthesis

Chemical Properties

Disodium dihydrogendiphosphate [7758-16-9], disodium diphosphate, acidic sodium pyrophosphate, Na2H2P2O7, Mr 221.97, d 2.31. Its solubility in water is 13g Na2H2P2O7/100g H2O at 20 °C, and 20g at 80°C. The pH of a 1% aqueous solution is 4.1. The usual commercial product is the anhydrous, nonhygroscopic salt in powder form. The hexahydrate, Na2H2P2O7.6H2O, d 1.85, crystallizes from aqueous solution below 27 °C. Above this temperature, it is converted to the anhydrous form. Disodium diphosphate is used as a (tropically stable) acid carrier in baking powder, for improvement of flow properties in flour, for pH regulation, and in dental care products for prevention of tartar formation.

Uses

Sodium Pyrophosphate is a leavening agent, preservative, sequestrant, and buffer which is mildly acidic with a ph of 4.1. It is moderately soluble in water, with a solubility of 15 g in 100 ml at 25°c. It is used in doughnuts and biscuits for its variable gas release rate during the mixing, bench action, and baking process. It is used in baking powder as a leavening agent. It is used in canned fish products to reduce the level of undesired struvite crystals (magnesium ammonium phosphate hexahydrate) by complexing the magnesium. It is used to sequester metals in processed potatoes. It is also termed sapp, sodium acid pyrophosphate, acid sodium pyrophosphate, disodium diphosphate, and disodium dihydrogen pyrophosphate.

Uses

Sodium Pyrophosphate Dibasic is anhydrous form, pyrophosphate salt used in buffers.

Preparation

Disodium dihydrogendiphosphate is produced from sodium dihydrogenmonophosphate by heating at 200-250℃：
Na2CO3+2H3PO4→2NaH2PO4+H2O+CO2↑
2NaH2PO4→Na2H2P2O7+H2O

General Description

The APP (amyloid precursor protein) gene is mapped to human chromosome 21q21.3. It encodes a integral membrane protein. APPα is a soluble protein generated by sequential cleavage with α and γ secretase.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Amyloid precursor protein α is an α-secretase-cleaved soluble protein that has been shown to have neuroprotective properties. It is derived from amyloid precursor protein. The protein consists of 612 amino acids. Several G protein-coupled receptors are known to activate α-secretase-dependent processing of APP. It has neuroprotective, neurogenic and neurotrophic functions. Amyloid precursor protein a also stimulates gene expression and protein expression.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. An irritant to skin, eyes, and mucous membranes. When heated to decomposition it emits toxic fumes of POx, and Na2O.

Sodium pyrophosphate(7758-16-9)Related Product Information

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