CYCLOPENTANECARBONITRILE Chemical Properties

Melting point:

−76 °C(lit.)

Boiling point:

67-68 °C10 mm Hg(lit.)

Density 

0.912 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.441(lit.)

Flash point:

132 °F

solubility 

Miscible with toluene.

form 

clear liquid

color 

Colorless to Almost colorless

BRN 

1098717

Exposure limits

NIOSH: IDLH 25 mg/m3

CAS DataBase Reference

4254-02-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

T

Risk Statements 

25-36/37/38

Safety Statements 

26-45

RIDADR 

UN 1992 3/PG 3

WGK Germany 

3

HazardClass 

6.1

PackingGroup 

II

HS Code 

29269090

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

CYCLOPENTANECARBONITRILE Usage And Synthesis

Chemical Properties

Clear colorless to faintly yellow liquid

Uses

Cyano substituted cyclopentane which can be converted into cyanohydrin glucosides by Passiflora morifolia and Turnera angustifolia.

Uses

Cyclopentanecarbonitrile is used as a substrate and reagent to investigate the specific activity of nitrile and amide hydrolyzing enzymes isolated from candida guilliermondii cells. It is also used to prepare cyclopentanecarboxamide by using tetrabutylammonium hydrogen sulfate as a catalyst in the presence of reagents such as aqueous hydrogen peroxide and sodium hydroxide.

General Description

Cyclopentanecarbonitrile is an alicyclic nitrile.

Purification Methods

Dissolve the nitrile in Et2O, wash it thoroughly with saturated aqueous K2CO3, dry (MgSO4) and distil it through a 10 cm Vigreux column (p 11). [McElvain & Stern J Am Chem Soc 77 457 1955, Bailey & Daly J Am Chem Soc 81 5397 1959, Beilstein 9 IV 14.]

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