Ethylenebis(oxyethylenenitrilo)tetraacetic acid
Ethylenebis(oxyethylenenitrilo)tetraacetic acid Basic information
- Product Name:
- Ethylenebis(oxyethylenenitrilo)tetraacetic acid
- Synonyms:
-
- 3,6-DIOXAOCTAMETHYLENEDINITRILOTETRAACETIC ACID
- 1,2-bis(2-dicarboxymethylaminoethoxy)ethane
- 12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-9-dioxa-3
- 6,9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-
- 9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-6
- ebonta
- ethylenedioxybis(ethyleneamino)tetraaceticacid
- ETHYLENE GLYCOL BIS-(BETA-AMINOETHYLETHER)-N,N,N',N'-TETRAACETIC
- CAS:
- 67-42-5
- MF:
- C14H24N2O10
- MW:
- 380.35
- EINECS:
- 200-651-2
- Product Categories:
-
- Analytical Chemistry
- Chelating Reagents
- Complexones
- EDTA Analogs
- Mol File:
- 67-42-5.mol
Ethylenebis(oxyethylenenitrilo)tetraacetic acid Chemical Properties
- Melting point:
- 241 °C (dec.)(lit.)
- Boiling point:
- 507.99°C (rough estimate)
- Density
- 1.2838 (rough estimate)
- refractive index
- 1.4590 (estimate)
- storage temp.
- room temp
- solubility
- 0.1 M NaOH: 0.1 M at 20 °C, clear, colorless
- pka
- 1.47±0.10(Predicted)
- form
- Crystalline Powder
- color
- White
- Water Solubility
- slightly soluble
- Merck
- 14,3529
- BRN
- 1717370
- CAS DataBase Reference
- 67-42-5(CAS DataBase Reference)
- EPA Substance Registry System
- Ethylenebis(oxyethylenenitrilo)tetraacetic acid (67-42-5)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 2
- RTECS
- AH3760000
- TSCA
- Yes
- HS Code
- 29225000
- Toxicity
- LD50 orally in Rabbit: 3587 mg/kg
MSDS
- Language:English Provider:Ethylenebis(oxyethylenenitrilo)tetraacetic acid
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
Ethylenebis(oxyethylenenitrilo)tetraacetic acid Usage And Synthesis
Description
Ethylenebis(oxyethylenenitrilo)tetraacetic acid is also named as Egtazic acid. It works as a chelating agent for the determination of calcium in the presence of magnesium.
Chemical Properties
White to slightly off-white powder
Uses
Pharmaceutic aid. EGTA.
Uses
Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid is a chelating agent used for making complexes, especially for calcium ions, which help to determine calcium in the presence of magnesium. It can be used experimentally for treating animals possessing cerium poisoning. It is useful in the separation of thorium from monazite. It also acts as a buffer and is used in protein purification.
Uses
A chelating agent useful for the determination of calcium in the presence of magnesium.
Definition
ChEBI: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.
Biological Activity
Calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also GLYCOL ETHERS.
storage
Room temperature
Purification Methods
Dissolve EGTA in aqueous NaOH, precipitate it by adding aqueous HCl, wash it with water and dry at 100o in vacuo.[Beilstein 4 IV 217.]
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Ethylenebis(oxyethylenenitrilo)tetraacetic acid(67-42-5)Related Product Information
- ETHYLENE
- Ethyl ethoxyacetate
- Iminodiacetic acid
- Ethylene glycol
- 2-Butoxyethanol
- 2-Phenoxyethanol
- 2-Butoxyethyl acetate
- Ethylene carbonate
- Folic acid
- Ethyl 2-(Chlorosulfonyl)acetate
- Citric acid
- GLYCOFUROL
- POLY(ETHYLENE-CO-ACRYLIC ACID)
- Ethylenediamine-N,N'-diacetic acid
- Hyaluronic acid
- Stearic acid
- 2-(Vinyloxy)ethanol
- ETHANE