5-Bromothiazole Chemical Properties

Melting point:

131-132 °C(Solv: ligroine (8032-32-4))

Boiling point:

80-81°C/18mm

Density 

1.835 at 25 °C

refractive index 

1.5955

Flash point:

170°F

pka

1.00±0.10(Predicted)

form 

Liquid

color 

Clear yellow to brown

Water Solubility 

Soluble in water.

Sensitive 

Moisture Sensitive

CAS DataBase Reference

3034-55-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-37/38-41-43

Safety Statements 

26-36/37/39

RIDADR 

NA 1993 / PGIII

WGK Germany 

3

HS Code 

29341000

5-Bromothiazole Usage And Synthesis

Uses

5-Bromothiazole is used as a pharmaceutical intermediate and performance material.

General Description

5-Bromothiazole is a monobromothiazole, which can be prepared via treatment of 2,5-dibromothiazole with sodium ethoxide followed by hydrogenation over spongy nickel.

Purification Methods

If bromothiazole is too coloured, then suspend it in dilute NaOH and steam distil it. Add NaCl to the aqueous distillate, extract it with Et2O, dry it (Na2SO4), evaporate and fractionate the residue in a vacuum. The HgCl2 salt crystallises from EtOH with m 148o (dec). [Beyerman et al. Recl Trav Chim, Pays Bas 73 330 1954, Beilstein 27 III/IV 962.]

5-Bromothiazole(3034-55-7)Related Product Information

• 2-(2-Aminothiazol-4-yl)glyoxylic acid
• 2-Mercaptobenzothiazole
• Fosthiazate
• 2,2'-Dithiobis(benzothiazole)
• Benzothiazole
• Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)
• Thiazole
• 5-Bromothiophene-2-carbaldehyde
• Ethyl 5-bromothiophene-2-carboxylate
• 2-BROMOTHIAZOLE
• 5-BROMO-2,4-DIMETHYL-1,3-THIAZOLE
• 5-BROMO-4-(TERT-BUTYL)-1,3-THIAZOL-2-AMINE HYDROBROMIDE
• 2-AMINO-5-BROMOTHIAZOLE,5-Bromothiazole-2-amine
• 2,5-DIBROMOTHIAZOLE
• 2-ACETAMIDO-5-BROMOTHIAZOLE,2-ACETYLAMINO-5-BROMOTHIAZOLE
• METHYL 2-AMINO-5-BROMOTHIAZOLE-4-CARBOXYLATE,2-AMINO-5-BROMOTHIAZOLE-4-CARBOXYLIC ACID METHYL ESTER
• 2-BROMOTHIAZOLE-5-METHANOL
• 2-Amino-5-bromothiazole monohydrobromide