ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyridine compound > Pyridine derivatives > 6,6'-DITHIODINICOTINIC ACID
6,6'-DITHIODINICOTINIC ACID
6,6'-DITHIODINICOTINIC ACID Basic information
- Product Name:
- 6,6'-DITHIODINICOTINIC ACID
- Synonyms:
-
- 6,6’-dithiobis-3-pyridinecarboxylicaci
- 6,6’-dithionicotinicacid
- carboxypyridinedisulfide
- cpds
- 6,6'-DITHIOBIS(3-PYRIDINECARBOXYLIC ACID)
- 6,6'-DITHIODINICOTINIC ACID
- 6-[(5-CARBOXY-2-PYRIDYL)DITHIO]NICOTINIC ACID
- 6,6'-DITHIODINICOTINIC ACID, TECH., 85%
- CAS:
- 15658-35-2
- MF:
- C12H8N2O4S2
- MW:
- 308.33
- EINECS:
- 239-729-6
- Product Categories:
-
- Heterocyclic Compounds
- Mol File:
- 15658-35-2.mol
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6,6'-DITHIODINICOTINIC ACID Chemical Properties
- Melting point:
- 263-265 °C(lit.)
- Boiling point:
- 584.2±50.0 °C(Predicted)
- Density
- 1.66±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 2.82±0.10(Predicted)
- color
- White to Light yellow
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 15658-35-2(CAS DataBase Reference)
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MSDS
- Language:English Provider:SigmaAldrich
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6,6'-DITHIODINICOTINIC ACID Usage And Synthesis
Chemical Properties
tan powder
Uses
6,6′-Dithiodinicotinic acid may be employed as:
- specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
- modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
- dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
- water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
- chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
- spectrophotometric determination of thiols and of total glutathione in human blood
General Description
6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported.
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