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6,6'-DITHIODINICOTINIC ACID

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6,6'-DITHIODINICOTINIC ACID Basic information

Product Name:
6,6'-DITHIODINICOTINIC ACID
Synonyms:
  • 6,6’-dithiobis-3-pyridinecarboxylicaci
  • 6,6’-dithionicotinicacid
  • carboxypyridinedisulfide
  • cpds
  • 6,6'-DITHIOBIS(3-PYRIDINECARBOXYLIC ACID)
  • 6,6'-DITHIODINICOTINIC ACID
  • 6-[(5-CARBOXY-2-PYRIDYL)DITHIO]NICOTINIC ACID
  • 6,6'-DITHIODINICOTINIC ACID, TECH., 85%
CAS:
15658-35-2
MF:
C12H8N2O4S2
MW:
308.33
EINECS:
239-729-6
Product Categories:
  • Heterocyclic Compounds
Mol File:
15658-35-2.mol
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6,6'-DITHIODINICOTINIC ACID Chemical Properties

Melting point:
263-265 °C(lit.)
Boiling point:
584.2±50.0 °C(Predicted)
Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
2.82±0.10(Predicted)
color 
White to Light yellow
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
15658-35-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
RTECS 
US5684700
HS Code 
2933399990

MSDS

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6,6'-DITHIODINICOTINIC ACID Usage And Synthesis

Chemical Properties

tan powder

Uses

6,6′-Dithiodinicotinic acid may be employed as:

  • specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
  • modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
  • dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
  • water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
  • chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
  • spectrophotometric determination of thiols and of total glutathione in human blood

General Description

6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported.

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