BETA-ZEARALENOL Chemical Properties

Melting point:

137-139°C

Flash point:

2℃

storage temp. 

2-8°C

solubility 

Acetone: Slightly Soluble; Methanol: Slightly Soluble

form 

powder

color 

White to off-white

BRN 

3653579

Stability:

Light Sensitive

Safety Information

Hazard Codes 

Xn,N,F

Risk Statements 

20/21/22-40-52/53-68/20/21/22-50-36-22-11

Safety Statements 

36/37-61-36-16

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

HS Code 

29322090

MSDS

• Language:English Provider:SigmaAldrich

BETA-ZEARALENOL Usage And Synthesis

Description

β-Zearalenol is a hepatic metabolite of zearalenone , a mycotoxin produced by fungi in food and animal feeds. It is a less potent agonist of estrogen receptors than the parent compound. However, β-zearalenol has pronounced effects on uterotropic activity and sperm acrosome reaction.

Chemical Properties

White Solid

Uses

Reactant involved in biological studies including:• ;Synthesis of amino glycoside nucleotides1• ;Enzymatic synthesis of glucuronides of zearalenone2• ;Derivatization of Zearalenone3,4,5

Uses

β-Zearalenol is a mycotoxin produced by several species of Fusarium. β-Zearalenol exhibits pronounced estrogenic activity, like other zearalenones. Contamination of grains by Fusarium species, notably maize, gives rise to high levels of zearalenol and is regarded as an important food quality issue for both human and animal health.

Uses

The more active Zearalenone (Z270500) metabolite.

Definition

ChEBI: Beta-Zearalenol is a macrolide.

References

[1] Y UENO  F T. alpha-Zearalenol, a major hepatic metabolite in rats of zearalenone, an estrogenic mycotoxin of Fusarium species.[J]. Journal of biochemistry, 1981, 89 2: 563-571. DOI: 10.1093/oxfordjournals.jbchem.a133232
[2] JOSé-MANUEL MOLINA-MOLINA . Assessment of estrogenic and anti-androgenic activities of the mycotoxin zearalenone and its metabolites using in vitro receptor-specific bioassays[J]. Food and Chemical Toxicology, 2014, 74: Pages 233-239. DOI: 10.1016/j.fct.2014.10.008
[3] ANGELA FILANNINO. Dose-response effects of estrogenic mycotoxins (zearalenone, alpha- and beta-zearalenol) on motility, hyperactivation and the acrosome reaction of stallion sperm.[J]. Reproductive Biology and Endocrinology, 2011, 9: 134. DOI: 10.1186/1477-7827-9-134
[4] DANIELA E. MARIN . Effects of zearalenone and its derivatives on the innate immune response of swine[J]. Toxicon, 2010, 56 6: Pages 956-963. DOI: 10.1016/j.toxicon.2010.06.020

BETA-ZEARALENOL(71030-11-0)Related Product Information

• ZEARALANONE
• Zeranol
• Methyl 2,4-dihydroxybenzoate
• 2,4-Dihydroxybenzoic acid
• Isopropyl salicylate
• 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
• Butyl salicylate
• Hexyl salicylate
• 2-Hydroxybenzoic acid octyl ester
• Octyl paraben
• Ethyl 2,4-dihydroxy-6-methylbenzoate
• Amyl salicylate
• ETHYL 2,4-DIHYDROXYBENZOATE
• BETA-ZEARALENOL
• 2-VINYL-BENZOIC ACID ETHYL ESTER
• 4-HYDROXYBENZOIC ACID SEC-BUTYL ESTER
• 4-HYDROXYBENZOIC ACID N-NONYL ESTER
• 6-METHYLSALICYLIC ACID ETHYL ESTER