1,3-Bis(chloromethyl)benzene Chemical Properties

Melting point:

33-35 °C(lit.)

Boiling point:

250-255 °C(lit.)

Density 

1.202 g/mL at 25 °C(lit.)

refractive index 

1.5544 (estimate)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

methanol: soluble1g/10 mL, clear, colorless

form 

powder to lump to clear liquid

color 

White or Colorless to Almost white or Almost colorless

Water Solubility 

hydrolysis

BRN 

2079898

InChI

InChI=1S/C8H8Cl2/c9-5-7-2-1-3-8(4-7)6-10/h1-4H,5-6H2

InChIKey

GRJWOKACBGZOKT-UHFFFAOYSA-N

SMILES

C1(CCl)=CC=CC(CCl)=C1

CAS DataBase Reference

626-16-4(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1,3-bis(chloromethyl)-(626-16-4)

EPA Substance Registry System

Benzene, 1,3-bis(chloromethyl)- (626-16-4)

Safety Information

Hazard Codes 

Xn,Xi,C

Risk Statements 

22-36/37/38-36-34

Safety Statements 

26-24/25-45-36/37/39-27

RIDADR 

UN 2811 6.1/PG 2

WGK Germany 

3

RTECS 

ZE4070000

F 

19

TSCA 

TSCA listed

HazardClass 

6.1

PackingGroup 

II

HS Code 

29036990

MSDS

• Language:English Provider:1,3-Bis(chloromethyl)benzene
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,3-Bis(chloromethyl)benzene Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

m-Xylene Dichloride is used in ionic liquids to increase their thermal stability as well as used as a reagent in C2-Symmetric Small Molecule Inhibitors.

Synthesis

The synthesis process of 1,3-bis(chloromethyl)benzene is as follows: (1) Reaction: 100 g of m-xylene and 0.1 g of 1-propyl-3-methylimidazole chloride salt were added to a reaction tank, and then 106.5 g of chlorine gas was passed into the reaction tank under the irradiation of LED light source, and the reaction was carried out for 6 h at 60 , to obtain m-dichlorobenzyl reaction solution with 70 wt% of m-dichlorobenzyl content; (2) Separation: m-dichlorobenzyl reaction solution was added to the separation tank, and layered at 35 , the upper layer of the solution into the reaction tank to continue the reaction, the lower layer of the solution is the m-dichlorobenzyl crude product; (3) Refining: add m-dichlorobenzyl crude product to the distillation column, carry out decompression distillation under 8mmHg, collect 145-149C fraction, get 116.59g m-dichlorobenzyl, the content of 99%, melting point is 33.5-34.8C.

1,3-Bis(chloromethyl)benzene(626-16-4)Related Product Information

• Dichloroethane
• Benzhydrylamine
• Musk xylene
• 1,2-Dichloro-4-(chloromethyl)benzene
• 1,3-Bis(bromomethyl)benzene
• Diethylstilbestrol
• 3-Chlorobenzyl chloride
• Sodium dichloroisocyanurate
• 4,4'-Bis(chloromethyl)-1,1'-biphenyl
• Xylene
• Quinclorac
• DIMETHYLTHEXYLSILYL CHLORIDE
• Thionyl chloride
• Chlorodimethylphenylsilane
• 4-(Chloromethyl)benzoic acid
• tert-Butyldimethylsilyl chloride
• Benzene
• bis(chloromethyl)benzene