1,3-Bis(chloromethyl)benzene Chemical Properties

Melting point:

33-35 °C(lit.)

Boiling point:

250-255 °C(lit.)

Density 

1.202 g/mL at 25 °C(lit.)

refractive index 

1.5544 (estimate)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

methanol: soluble1g/10 mL, clear, colorless

form 

powder to lump to clear liquid

color 

White or Colorless to Almost white or Almost colorless

Water Solubility 

hydrolysis

BRN 

2079898

InChI

InChI=1S/C8H8Cl2/c9-5-7-2-1-3-8(4-7)6-10/h1-4H,5-6H2

InChIKey

GRJWOKACBGZOKT-UHFFFAOYSA-N

SMILES

C1(CCl)=CC=CC(CCl)=C1

CAS DataBase Reference

626-16-4(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1,3-bis(chloromethyl)-(626-16-4)

EPA Substance Registry System

Benzene, 1,3-bis(chloromethyl)- (626-16-4)

Safety Information

Hazard Codes 

Xn,Xi,C

Risk Statements 

22-36/37/38-36-34

Safety Statements 

26-24/25-45-36/37/39-27

RIDADR 

UN 2811 6.1/PG 2

WGK Germany 

3

RTECS 

ZE4070000

F 

19

TSCA 

TSCA listed

HazardClass 

6.1

PackingGroup 

II

HS Code 

29036990

MSDS

• Language:English Provider:1,3-Bis(chloromethyl)benzene
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,3-Bis(chloromethyl)benzene Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

m-Xylene Dichloride is used in ionic liquids to increase their thermal stability as well as used as a reagent in C2-Symmetric Small Molecule Inhibitors.

Synthesis

The synthesis process of 1,3-bis(chloromethyl)benzene is as follows: (1) Reaction: 100 g of m-xylene and 0.1 g of 1-propyl-3-methylimidazole chloride salt were added to a reaction tank, and then 106.5 g of chlorine gas was passed into the reaction tank under the irradiation of LED light source, and the reaction was carried out for 6 h at 60 ??, to obtain m-dichlorobenzyl reaction solution with 70 wt% of m-dichlorobenzyl content; (2) Separation: m-dichlorobenzyl reaction solution was added to the separation tank, and layered at 35 ??, the upper layer of the solution into the reaction tank to continue the reaction, the lower layer of the solution is the m-dichlorobenzyl crude product; (3) Refining: add m-dichlorobenzyl crude product to the distillation column, carry out decompression distillation under 8mmHg, collect 145-149??C fraction, get 116.59g m-dichlorobenzyl, the content of 99%, melting point is 33.5-34.8??C.

1,3-Bis(chloromethyl)benzene(626-16-4)Related Product Information

• Dichloroethane
• Benzhydrylamine
• Musk xylene
• 1,2-Dichloro-4-(chloromethyl)benzene
• 1,3-Bis(bromomethyl)benzene
• Diethylstilbestrol
• 3-Chlorobenzyl chloride
• tert-Butyldimethylsilyl chloride
• Sodium dichloroisocyanurate
• 4,4'-Bis(chloromethyl)-1,1'-biphenyl
• Xylene
• Thionyl chloride
• Chlorodimethylphenylsilane
• 4-(Chloromethyl)benzoic acid
• Quinclorac
• DIMETHYLTHEXYLSILYL CHLORIDE
• Benzene
• bis(chloromethyl)benzene