1,2-Dibromopropane Chemical Properties

Melting point:

-55 °C

Boiling point:

140-142 °C(lit.)

Density 

1.937 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.519(lit.)

Flash point:

35 °C

storage temp. 

Flammables area

solubility 

organic solvents: miscible

form 

clear liquid

color 

Colorless to Light yellow to Light orange

Water Solubility 

slightly soluble

Merck 

14,7853

BRN 

1718884

Dielectric constant

4.2999999999999998

Stability:

Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, magnesium.

CAS DataBase Reference

78-75-1(CAS DataBase Reference)

NIST Chemistry Reference

Propane, 1,2-dibromo-(78-75-1)

EPA Substance Registry System

1,2-Dibromopropane (78-75-1)

Safety Information

Hazard Codes 

Xn

Risk Statements 

10-20/22-36/37/38-20/21/22-40

Safety Statements 

23-24/25-36/37/39-26-16-45-27

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

RTECS 

TX8574000

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29033036

Hazardous Substances Data

78-75-1(Hazardous Substances Data)

MSDS

• Language:English Provider:Propylene dibromide
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,2-Dibromopropane Usage And Synthesis

Chemical Properties

1,2-Dibromopropane is considered non-flammable and non-explosive liquid.

Uses

1,2-Dibromopropane is used in organic synthesis and solvent. It was used to study the effect of reductant concentration, reductant contact time and suspension pH on reductive dechlorination of carbon tetrachloride by soil manipulated with Fe(II) and HS-. It was used as internal standard during the determination of nitrogenous disinfection byproduct trichloronitromethane by gas chromatography mass spectrometry.

Application

Photodissociation dynamics of 1,2-dibromopropane at 234 and 265 nm has been investigated by using velocity map ion imaging method. 1,2-Dibromopropane was used to study the effect of reductant concentration, reductant contact time and suspension pH on reductive dechlorination of carbon tetrachloride by soil manipulated with Fe(II) andHS-. It was used as internal standard during the determination of nitrogenous disinfection byproduct trichloronitromethane by gas chromatography mass spectrometry.

Preparation

1,2-Dibromopropane is synthesized from bromopropane by bromination.
First mix bromopropane and iron powder, heat to 40-50°C, slowly add bromine, and continue to reflux for 2h after adding. Then, the iron slag was filtered off, and the filtrate was washed several times with water, once with 5% sodium carbonate solution, and then with 5% sodium thiosulfate solution to remove free bromine. Dry with anhydrous calcium chloride. Fractional distillation, collecting 139-142 ℃ fraction is the finished product of 1,2-dibromopropane.

General Description

1,2-dibromopropane is a colorless liquid. Prepared from propyl bromide and Br in the presence of AlCl3 or AlBr3. (NTP, 1992)

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Halogenated aliphatic compounds, such as 1,2-Dibromopropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. 1,2-Dibromopropane is considered nonflammable.

Fire Hazard

1,2-Dibromopropane is considered non-flammable.

Biochem/physiol Actions

1,2-Dibromopropane induces hepatotoxicity and immunotoxicity in female BALB/c mice.

1,2-Dibromopropane(78-75-1)Related Product Information

• 2-Bromopropane
• 1-Bromopropane
• 2,3-Dibromopropionic acid
• PROPYLENE
• 1,3-Dibromo-5,5-dimethylhydantoin
• meso-2,3-Dibromosuccinic acid
• 1,2-Dibromoethane
• PROPYLENE GLYCOL
• Ethyl 2,3-dibromopropionate
• (1,2-DIBROMOETHYL)BENZENE
• 2-Bromoisobutyryl Bromide
• Hexabromocyclododecane
• 1,2-Dibromobutane
• 2,3-DIBROMOBUTANE
• 3-Chloro-1,2-dibromopropane 98%,3-CHLORO-1,2-DIBROMOPROPANE,1-CHLORO-2 3-DIBROMOPROPANE
• 1,3-Dibromopropane
• 2,3-Dibromopropionyl chloride
• 1,2-DIBROMO-1,2-DIPHENYLETHANE