ROSAMICIN Chemical Properties

Melting point:

119-122°

alpha 

D26 -35° (ethanol)

Boiling point:

640.04°C (rough estimate)

Density 

1.1598 (rough estimate)

refractive index 

1.6310 (estimate)

storage temp. 

2-8°C

solubility 

methanol: 10 mg/mL, clear, light yellow

form 

solid

biological source

Micromonospora rosaria

Merck 

13,8342

BRN 

1633003

InChIKey

IUPCWCLVECYZRV-JZMZINANSA-N

SMILES

[H]C(=O)C[C@H]1C[C@@H](C)C(=O)\C=C\[C@]2(C)O[C@@]2([H])[C@H](C)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]1O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

Safety Statements 

26-36

WGK Germany 

3

RTECS 

JG6800000

F 

10

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral

Toxicity

LD50 in mice (mg/kg): 625 s.c.; 350 i.p.; 155 i.v. (Wagman)

MSDS

• Language:English Provider:SigmaAldrich

ROSAMICIN Usage And Synthesis

Uses

Antibacterial.

Definition

ChEBI: A macrolide antibiotic with activity against Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis.

Biochem/physiol Actions

Macrolide antibiotic similar to erythromycin, and with a similar spectrum of bactericidal activity. Against a wide variety of anaerobes, rosamicin is at least as potent as, and in some cases more potent than, erythromycin.

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