3-PHENYLSALICYLIC ACID Chemical Properties

Melting point:

186°C

Boiling point:

314.35°C (rough estimate)

Density 

1.2500

refractive index 

1.5090 (estimate)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

2.84±0.10(Predicted)

color 

White to Off-White

Stability:

Hygroscopic

EPA Substance Registry System

[1,1'-Biphenyl]-3-carboxylic acid, 2-hydroxy- (304-06-3)

Safety Information

Safety Statements 

22-24/25

RTECS 

VO5600000

TSCA 

TSCA listed

HS Code 

2918.29.7500

3-PHENYLSALICYLIC ACID Usage And Synthesis

Uses

2''-Hydroxybiphenyl-3-carboxylic Acid can be used as antibacterial agents.

Safety Profile

Poison by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fume

Synthesis

3-Phenylsalicylic acid can be prepared from 2-phenylphenol in one step.

Purification Methods

Dissolve the acid in ca 1 equivalent of saturated aqueous Na2CO3, filter and precipitate it by adding 0.8 equivalents of M HCl. Crystallise it from ethylene dichloride (charcoal), and sublime it at 0.1mm. [Brooks et al. J Chem Soc 661 1961.]

3-PHENYLSALICYLIC ACID(304-06-3)Related Product Information

• 3-PHENYLSALICYLIC ACID
• O-phenylsalicylic acid
• Diflunisal
• xenysalate
• Salicylic acid
• 2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID
• 1,1'-BIS(2-HYDROXY-3-NAPHTHOIC ACID)
• RARECHEM AL BE 1402
• (R)-(+)-DIMETHYL-2 2'-DIHYDROXY-1 1'-BI&
• benastatin B
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• 5-PHENYLSALICYLIC ACID POR [R]
• bequinostatin A
• AURORA KA-6266
• 5-Chloro-2-hydroxy-3-biphenylcarboxylic acid, 2-(diisopropylamino)ethyl ester, hydrochloride
• RARECHEM AL BI 1402
• 1,1'-BIS(2-HYDROXY-3,6-NAPHTHALENEDICARBOXYLIC ACID)
• Isoporiolide