2'-FLUORO-6'-HYDROXYACETOPHENONE Chemical Properties

Boiling point:

224.0±20.0 °C(Predicted)

Density 

1.25g/ml

refractive index 

1.534

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

liquid

pka

9.17±0.10(Predicted)

color 

Clear, faint lime

Safety Information

Hazard Codes 

Xi

Hazard Note 

Irritant

HS Code 

2914500090

2'-FLUORO-6'-HYDROXYACETOPHENONE Usage And Synthesis

Preparation

Preparation by reaction of boron tribromide on 2-fluoro-6- methoxyacetophenone (I) in methylene chloride at ?65° to ?80° (56%). The precursor (I) was obtained by reaction of methyl magnesium iodide on 2-fluoro-6-methoxybenzonitrile in refluxing toluene (quantitative yield).

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