THIOBENZAMIDE Chemical Properties

Melting point:

113-117 °C (lit.)

Boiling point:

180 °C

Density 

1.1364 (rough estimate)

refractive index 

1.5500 (estimate)

Flash point:

120°C

storage temp. 

Sealed in dry,Room Temperature

form 

Crystalline Powder

pka

12.68±0.29(Predicted)

color 

yellow

Water Solubility 

Slightly soluble in water.

BRN 

606021

CAS DataBase Reference

2227-79-4(CAS DataBase Reference)

EPA Substance Registry System

Benzenecarbothioamide (2227-79-4)

Safety Information

Hazard Codes 

T

Risk Statements 

25

Safety Statements 

45-24/25

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

CV5860000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29309090

Toxicity

mnt-mus-orl 180 mmol/kg MUREAV 192,141,87

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

THIOBENZAMIDE Usage And Synthesis

Chemical Properties

Yellowish-green crystalline powder

Uses

Thiobenzamide is useful for the preparation of amide and amidine adducts. It is also used to prepare 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides. Further, it acts as a raw material in organic synthesis.

Uses

Thiobenzamide was used to prepare amide and amidine adducts. It was also used in the synthesis of 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides.

Definition

ChEBI: Thiobenzamide is a member of benzenes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 962, 1976 DOI: 10.1021/jo00868a013
Synthesis, p. 917, 1978 DOI: 10.1055/s-1978-24939

Safety Profile

Poison by ingestion. Moderatelytoxic by intraperitoneal route. Questionable carcinogenwith experimental tumorigenic data. Mutation datareported. When heated to decomposition it emits verytoxic fumes of NOx and SOx.

THIOBENZAMIDE(2227-79-4)Related Product Information

• 4-Methyl(thiobenzamide),97%,4-METHYL(THIOBENZAMIDE)
• 2,6-Dichlorothiobenzamide
• 4-(Trifluoromethyl)thiobenzamide
• 2-Chlorothiobenzamide
• THIOBENZAMIDE
• Vanitiolide
• 4-METHOXYTHIOBENZAMIDE
• 3-CHLORO-4-FLUOROTHIOBENZAMIDE
• 6-Methylpyridazin-3(2H)-one
• 4-Chlorothiobenzamide
• 3-(TRIFLUOROMETHYL)THIOBENZAMIDE
• 3-CHLORO-THIOBENZAMIDE
• 4-(1,2,3-THIADIAZOL-4-YL)BENZENE-1-CARBOTHIOAMIDE
• 4-(1,3-DIOXOLAN-2-YL)BENZENE-1-CARBOTHIOAMIDE
• 1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID
• 3-(1H-PYRROL-1-YL)BENZENE-1-CARBOTHIOAMIDE
• 3-HYDROXY-THIOBENZAMIDE
• TC-NBT