3-HYDROXY-3-METHYL-D3-PENTANEDIOIC ACID Chemical Properties

Melting point:

104-108°C

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

Methanol (Slightly), Water (Slightly)

form 

solid

color 

White to Off-White

Safety Information

WGK Germany 

2

3-HYDROXY-3-METHYL-D3-PENTANEDIOIC ACID Usage And Synthesis

Uses

Meglutol-d3 is the deuterium labeled Meglutol[1]. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110

3-HYDROXY-3-METHYL-D3-PENTANEDIOIC ACID(59060-36-5)Related Product Information

• DIMETHYL SULFOXIDE-D6
• SEC-BUTANOL-1,1,1-D3
• BUTYRIC-4,4,4-D3 ACID
• 3-HYDROXY-3-METHYL-D3-PENTANEDIOIC ACID
• TERT-BUTANOL-1,1,1-D3