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3,5-Dimethyl-4-hydroxybenzaldehyde

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3,5-Dimethyl-4-hydroxybenzaldehyde Basic information

Product Name:
3,5-Dimethyl-4-hydroxybenzaldehyde
Synonyms:
  • BUTTPARK 96\57-68
  • 4-hydroxy-3,5-dimethyl-benzaldehyd
  • 3,5-DIMETHYL-4-HYDROXYBENZALDEHYDE
  • 4-HYDROXY-3,5-DIMETHYLBENZALDEHYDE
  • Syringnldehyde
  • 3,5-Dimethyl-4-Hydorxybenzaldehyde
  • 3,5-Dimethyl-4-Hydroxybenzalde
  • 4-Hydroxy-3,5-dimethylbenzaldehyde, TECH
CAS:
2233-18-3
MF:
C9H10O2
MW:
150.17
EINECS:
218-774-5
Product Categories:
  • Aromatic Aldehydes & Derivatives (substituted)
  • Aldehydes
  • Phenyls & Phenyl-Het
  • Benzaldehyde
  • API intermediates
  • Phenyls & Phenyl-Het
  • Alcohols and Derivatives
  • Carbonyl Compounds
  • Building Blocks
  • C9
  • Chemical Synthesis
  • Organic Building Blocks
Mol File:
2233-18-3.mol
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3,5-Dimethyl-4-hydroxybenzaldehyde Chemical Properties

Melting point:
112-114 °C(lit.)
Boiling point:
231.72°C (rough estimate)
Density 
1.0858 (rough estimate)
refractive index 
1.5180 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
8.48±0.23(Predicted)
color 
Off-White to Pale Yellow
Sensitive 
Air Sensitive
BRN 
1908717
CAS DataBase Reference
2233-18-3(CAS DataBase Reference)
EPA Substance Registry System
Benzaldehyde, 4-hydroxy-3,5-dimethyl- (2233-18-3)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29124990

MSDS

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3,5-Dimethyl-4-hydroxybenzaldehyde Usage And Synthesis

Chemical Properties

tan to light brown crystalline powder

Uses

3,5-Dimethyl-4-hydroxybenzaldehyde is used as a reagent in the synthesis of new diarylaniline analogs which were evaluated as HIV-1 non-nucleoside reverse transcriptase inhibitor agents. Also used in preparation of novel benzimidazole-5-carboxylate and its hydrazone derivatives which show potential for use as anti-inflammatory and antimicrobial agents.

Synthesis Reference(s)

Synthesis, p. 747, 1984 DOI: 10.1055/s-1984-30956
Tetrahedron Letters, 31, p. 2607, 1990 DOI: 10.1016/0040-4039(90)80137-B

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