3,6-Dichlorophthalic anhydride Chemical Properties

Melting point:

188-190 °C(lit.)

Boiling point:

339.1°C (rough estimate)

Density 

1.5974 (estimate)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly, Heated)

form 

Solid

color 

White to Off-White

BRN 

164697

Stability:

Moisture Sensitive

CAS DataBase Reference

4466-59-5(CAS DataBase Reference)

NIST Chemistry Reference

3,6-Dichloro-phthalic anhydride(4466-59-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

10-21

MSDS

• Language:English Provider:SigmaAldrich

3,6-Dichlorophthalic anhydride Usage And Synthesis

Chemical Properties

off-white to white powder

Uses

3,6-Dichlorophthalic Anhydride is an intermediate in the synthesis of phthalic compounds, phthalazines, and quinones with antimicrobial activity.

Purification Methods

Boil the anhydride in xylene (allowing any vapours which would contain H2O to be removed, e.g. Dean and Stark trap), which causes any acid present to dehydrate to the anhydride, and cool. Recrystallise it from xylene [Villiger Chem Ber 42 3539 1909, Fedoorow Izv Akad Nauk SSSR Otd Khim Nauk 397 1948, Chem Abstr 1585 1948]. [Beilstein 17/11 V 260.]

3,6-Dichlorophthalic anhydride(4466-59-5)Related Product Information

• CIS-BUTENEDIOIC ANHYDRIDE
• Isatoic Anhydride
• cis-1,2,3,6-Tetrahydrophthalic anhydride
• Dibutyl phthalate
• Tetrachlorophthalic anhydride
• PHTHALAMIDE
• O-Phthalimide
• Succinic anhydride
• Glutaric anhydride
• Phthalic anhydride
• Phthalonitrile
• 4-Chlorophthalic anhydride
• 3-Nitrophthalic anhydride
• Dimethyl phthalate
• Phthalhydrazide
• Trifluoromethanesulfonic anhydride
• 3-Fluorophthalic anhydride
• 2-Chlorobenzoic acid