Oleclumab
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Oleclumab Chemical Properties
- storage temp.
- Store at -20°C
- form
- Liquid
- color
- Colorless to light yellow
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Oleclumab Usage And Synthesis
Uses
The CD73-antagonist antibody oleclumab inhibits cell surface-exposed CD73 and is currently undergoing clinical testing for cancer immunotherapy.
in vivo
Oleclumab (10 mg/kg; ip; every 3 days for 4 doses) increases the proportion of activated CD8+ lymphocyte populations in the mouse Balb/c syngeneic CT26 colon cancer tumor model. And Oleclumab significantly inhibits tumor growth[2].
| Animal Model: | Murine, Balb/c, syngeneic CT26 colon carcinoma tumor model[2] |
| Dosage: | 10 mg/kg |
| Administration: | ip; 2 time per week, for 2 weeks |
| Result: | Inhibited tumor growth by 50% or greater from study day 7 to study day 16 when compared with isotype control antibody-treated groups. |
OleclumabSupplier
Shanghai YuanYe Biotechnology Co., Ltd.
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- 021-61312847; 18021002903
- 3008007409@qq.com
ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
- 2853530910@QQ.com
Guangzhou Hongyuan Chemical Co.,Ltd
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- 15817493340
- 981810490@qq.com
Wuhan Chemstan Biotechnology Co., Ltd.
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- 027-65317797 15926423062
- 422450190@qq.com
Bide Pharmatech Ltd.
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- 400-1647117 13681763483
- product02@bidepharm.com