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Thalidomide-O-PEG4-Propargyl

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Thalidomide-O-PEG4-Propargyl Basic information

Product Name:
Thalidomide-O-PEG4-Propargyl
Synonyms:
  • Thalidomide-O-PEG4-Propargyl
  • 4-((3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
  • Thalidomide-PEG4-Propargyl
  • E3 Ligase Ligand-Linker Conjugates,Thalidomide-PEG-4-Propargyl,inhibit,Inhibitor,Thalidomide PEG4 Propargyl,ThalidomidePEG4Propargyl
  • 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(3,6,9,12-tetraoxapentadec-14-yn-1-yloxy)-
CAS:
2098799-77-8
MF:
C24H28N2O9
MW:
488.49
Product Categories:
  • peg
Mol File:
2098799-77-8.mol
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Thalidomide-O-PEG4-Propargyl Chemical Properties

Boiling point:
673.9±55.0 °C(Predicted)
Density 
1.320±0.06 g/cm3(Predicted)
solubility 
Soluble in Water, DMF, DCM, DMSO
pka
10.70±0.40(Predicted)
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Safety Information

HS Code 
2933998090
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Thalidomide-O-PEG4-Propargyl Usage And Synthesis

Description

Thalidomide-O-PEG4-Propargyl is synthesized compound that incorporates the Thalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology, Propargyl is reactive with azide molecule in the presence of Cu catalyst.

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