-alkylC5-amine Chemical Properties

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

form 

Solid

color 

Light yellow to green yellow

-alkylC5-amine Usage And Synthesis

Uses

Thalidomide-NH-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

-alkylC5-amine(2375194-03-7)Related Product Information

• Thalidomide-O-amido-C2-NH2
• 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
• 2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione
• Thalidomide-NH-C6-NH2 TFA
• 4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
• E3 ligase Ligand-Linker Conjugates 15
• Thalidomide-O-amido-C2-NH2
• Thalidomide-NH-PEG2-C2-NH2 hydrochloride
• Thalidomide-NH-PEG2-C2-NH2 (TFA)
• Thalidomide-NH-C4-NH-Boc
• Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
• Thalidomide-NH-C4-NH2 TFA
• 4-[(4-Aminobutyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
• Pomalidomide-C6-NH2?hydrochloride
• 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
• β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
• Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
• 4-((4-azidobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione