Cyclopentylamine Chemical Properties

Melting point:

-85°C

Boiling point:

106-108 °C(lit.)

Density 

0.863 g/mL at 25 °C(lit.)

vapor pressure 

26.72hPa at 20℃

refractive index 

n20/D 1.450(lit.)

Flash point:

63 °F

storage temp. 

Flammables area

form 

Liquid

pka

pK1:10.65(+1) (25°C)

color 

Clear

explosive limit

1.3-9.40%(V)

Water Solubility 

MISCIBLE

BRN 

635706

LogP

0.83 at 20℃

CAS DataBase Reference

1003-03-8(CAS DataBase Reference)

NIST Chemistry Reference

Cyclopentanamine(1003-03-8)

EPA Substance Registry System

Cyclopentanamine (1003-03-8)

Safety Information

Hazard Codes 

F,Xi,T

Risk Statements 

11-37/38-43-34-25-20

Safety Statements 

16-45-36/37/39-25-26

RIDADR 

UN 2733 3/PG 2

WGK Germany 

3

RTECS 

GY8452000

F 

8-10-23

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29213099

MSDS

• Language:English Provider:Cyclopentylamine
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Cyclopentylamine Usage And Synthesis

Chemical Properties

a colorless liquid with an ammoniacal odor.

Uses

Cyclopentylamine acts as an important raw material and intermediate used in organic synthesis and pharmaceuticals. Further, it serves as chemokine receptor 2 antagonists. It acts as a ligand in coordination chemistry and forms cis-dichlorobis(cyclopentylamine)platinum(II) complex.

Preparation

Cyclopentylamine is produced from cyclopentanone and ammonia over nickel catalysts at 20 MPa and 150 – 200℃ in the presence of circulating hydrogen over a fixedbed catalyst.

Application

Cyclopentylamine is used in small amounts as an intermediate for the potato and rice fungizide pencycuron (Bayer, Nihon Tokushu, Noyaku Seizo).

Flammability and Explosibility

Highly flammable

Purification Methods

The amine may contain H2O or CO2 in the form of carbamate salt. Dry it over KOH pellets and then distil it from a few pellets of KOH. Store it in a dark, dry CO2-free atmosphere. It is characterised as the thiocyanate salt m 94.5o. The benzenesulfonyl derivative has m 68.5-69.5o. [Roberts & Chambers J Am Chem Soc 73 5030 1951, Bollinger et al. J Am Chem Soc 75 1729 1953, Beilstein 12 IV 4.]

Cyclopentylamine(1003-03-8)Related Product Information

• 1,3-Cyclopentadiene
• METHYLCYCLOPENTADIENE DIMER
• Propyzamide
• Cyclopentanone
• Cyclohexylamine
• Amylamine
• Cyprodinil
• N-METHYL CYCLOPENTYLAMINE
• CYCLOPENTYL ISOTHIOCYANATE
• (2R)-Bornane-10,2-sultam
• 3-(CYCLOPENTYLAMINO)PROPIONITRILE
• NITROCYCLOPENTANE
• (R)-(+)-BORNYLAMINE
• Cycloleucine
• SOLANIDINE
• N,N-Dimethyl Cyclopentylamine
• Cyclopentane
• N6-CYCLOPENTYLADENOSINE