1,3-Diaminopropane Chemical Properties

Melting point:

-12 °C

Boiling point:

140 °C(lit.)

Density 

0.888 g/mL at 25 °C(lit.)

vapor pressure 

<8 mm Hg ( 20 °C)

refractive index 

n20/D 1.458(lit.)

Flash point:

120 °F

storage temp. 

Store below +30°C.

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Liquid

pka

10.94(at 10℃)

color 

Clear

PH

>12 (100g/l, H2O, 20℃)

explosive limit

2.8-15.2%(V)

Water Solubility 

SOLUBLE

Sensitive 

Air Sensitive

BRN 

605277

Dielectric constant

9.6（Ambient）

Stability:

Stable. Hygroscopic. Flammable - readily forms explosive mixtures with air. Incompatible with acid anhydrides, acid chlorides, acids, strong oxidizing agents.

LogP

-1.05 at 25℃

CAS DataBase Reference

109-76-2(CAS DataBase Reference)

NIST Chemistry Reference

1,3-Propanediamine(109-76-2)

EPA Substance Registry System

1,3-Diaminopropane (109-76-2)

Safety Information

Hazard Codes 

T,C

Risk Statements 

10-22-24-35

Safety Statements 

26-36/37/39-45-25-16

RIDADR 

UN 2922 8/PG 2

WGK Germany 

2

RTECS 

TX6825000

F 

34

Autoignition Temperature

662 °F

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29212900

Toxicity

LD50 orally in Rabbit: 700 mg/kg LD50 dermal Rabbit 200 mg/kg

MSDS

• Language:English Provider:1,3-Diaminopropane
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
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1,3-Diaminopropane Usage And Synthesis

Chemical Properties

colourless liquid

Uses

1,3-Diaminopropane is commonly used in the preparation of cholinesterase inhibitors and thrombosis inhibitors. It is also used as a polymer cross linkage agent, polyurethane extender and spray coatings. It is involved in the preparation of agrochemicals and pharmaceutical intermediates. Further, it acts as a building block in the synthesis of heterocyclic compounds, which finds application in textile finishing. In addition to this, it is used as a ligand and form coordination complexes. 1,3-Diaminopropane is also utilized for the production of a chelating agent used in the photo industry and for anticorrosion agents.

Production Methods

1,3-Diaminopropane is produced in a twostage continuous process, under a pressure of 10 – 20 MPa. In a first reactor, acrylonitrile reacts with excess ammonia at 70 – 100 ℃ to give 2-aminopropionitrile and bis(cyanoethyl) amine. The mixture of aminonitriles is then hydrogenated in a downstream reactor over a fixed-bed catalyst (cobalt or nickel) at 60 – 120 ℃ to give 1,3-diaminopropane and bis (aminopropyl)amine. The yield of 1,3- diaminopropane can be increased by adding a polar solvent and water or by using a large excess of ammonia.

Definition

ChEBI: An alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3.

General Description

Water-white mobile liquid with an odor of amine.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

1,3-Diaminopropane is heat sensitive. 1,3-Diaminopropane may react with oxidizing agents.

Health Hazard

ACUTE/CHRONIC HAZARDS: 1,3-Diaminopropane is a strong irritant to eyes and skin: corrosive HAZARDOUS DECOMPOSITION PRODUCTS.

Fire Hazard

1,3-Diaminopropane is a flammable liquid.

Flammability and Explosibility

Flammable

Safety Profile

Poison by ingestion and skin contact. Experimental teratogenic effects. A severe skin and eye irritant. Flammable liquid when exposed to heat, sparks, or flame. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.

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