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ChemicalBook >  Product Catalog >  Organic Chemistry >  Alcohols,Phenols,Phenol alcohols >  Phenol derivatives >  2,3-Dichlorophenol

2,3-Dichlorophenol

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2,3-Dichlorophenol Basic information

Product Name:
2,3-Dichlorophenol
Synonyms:
  • 2,3-DICHLOROPHENOL
  • 2,3-dichloro-pheno
  • 2 3-DICHLOROPHENOL 1000MG NEAT
  • 2,3-DICHLOR-PHENOL
  • 2,3-Dichlorophenol,98+%
  • Phenol, 2,3-dichloro-
  • 2,3-DICHLOROPHENOL 99+%
  • 2,3-two chlorophenol
CAS:
576-24-9
MF:
C6H4Cl2O
MW:
163
EINECS:
209-399-8
Product Categories:
  • alcohol| alkyl chloride
  • Phenol&Thiophenol&Mercaptan
  • Chlorine Compounds
  • Phenols
  • Alphabetic
  • D
  • Organic Building Blocks
  • Oxygen Compounds
  • DIA - DIC
  • Building Blocks
  • C6 to C8
  • Chemical Synthesis
  • Organic Building Blocks
  • Oxygen Compounds
  • Aromatic Phenols
Mol File:
576-24-9.mol
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2,3-Dichlorophenol Chemical Properties

Melting point:
56 °C
Boiling point:
214 °C
Density 
1.40 g/cm3 (25℃)
refractive index 
1.4430 (estimate)
Flash point:
115 °C
storage temp. 
0-6°C
solubility 
3600mg/l (experimental)
pka
7.44(at 25℃)
color 
White to Light red to Green
Water Solubility 
<0.1 g/100 mL at 20 ºC
BRN 
2043615
Stability:
Stable. Incompatible with oxidizing agents, acid chlorides, acid anhydrides.
CAS DataBase Reference
576-24-9(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 2,3-dichloro-(576-24-9)
EPA Substance Registry System
2,3-Dichlorophenol (576-24-9)
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Safety Information

Hazard Codes 
Xn,Xi,N,C
Risk Statements 
22-36/38-51/53-34
Safety Statements 
26-28-61-45-36/37/39
RIDADR 
UN 2020 6.1/PG 3
WGK Germany 
3
RTECS 
SK8450000
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29081000
Hazardous Substances Data
576-24-9(Hazardous Substances Data)

MSDS

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2,3-Dichlorophenol Usage And Synthesis

Chemical Properties

2,3-dichlorophenol appears as light brown crystalline solid. Soluble in ether, chloroform and hot ethanol, insoluble in water and benzene.

Uses

2,3-Dichlorophenol is a chemical reagent used in the synthesis of a small molecule IL-2 inhibitor.

Preparation

2,3-Dichlorophenol is obtained from 1,2,3-trichlorobenzene by sulfonation to salt and high pressure hydrolysis to 3,4-dichloro-2-hydroxybenzenesulfonic acid, then hydrolyzed by sulfuric acid to remove the sulfonic acid group.

General Description

Brown crystals (from ligroin, benzene). Taste threshold concentration 0.00004 mg/L. Odor threshold concentration 0.03 mg/L.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,3-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 2,3-Dichlorophenol are not available. 2,3-Dichlorophenol is probably combustible.

Purification Methods

Crystallise it from ether. [Beilstein 6 IV 883.]

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