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(S)-(+)-Epichlorohydrin

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(S)-(+)-Epichlorohydrin Basic information

Product Name:
(S)-(+)-Epichlorohydrin
Synonyms:
  • (S)-(+)-2-(Chloromethyl)oxirane (S)-Epichlorohydrin (S) 1-Chloro-2,3-epoxypropane (S)-3-Chloropropylene Oxide (S)-Chloromethyloxirane (S)-(+)-1-Chloro-2,3-epoxypropane 2-(Chloromethyl)oxirane
  • (S)-(+)-CHLOROMETHYLOXIRANE
  • (S)-CHLOROMETHYLOXIRANE
  • (S)-3-CHLOROPROPYLENE OXIDE
  • S(+)-2-(CHLOROMETHYL)OXIRANE
  • (S)-(+)-1-CHLORO-2,3-EPOXYPROPANE
  • (S)-1-CHLORO-2,3-EPOXYPROPANE
  • OXIRANE, (CHLOROMETHYL)-, (2S)-
CAS:
67843-74-7
MF:
C3H5ClO
MW:
92.52
EINECS:
614-150-5
Product Categories:
  • Chiral Building Blocks
  • Glycidyl Compounds, etc. (Chiral)
  • Oxiranes
  • Simple 3-Membered Ring Compounds
  • Synthetic Organic Chemistry
  • Chiral Compound
  • Industrial/Fine Chemicals
  • chiral
  • CHIRAL COMPOUNDS
  • Chiral Reagents
  • Heterocycles
  • Mutagenesis Research Chemicals
  • Heterocyclic Acids
  • 67843-74-7
  • hnw00001
Mol File:
67843-74-7.mol
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(S)-(+)-Epichlorohydrin Chemical Properties

Melting point:
−57 °C(lit.)
Boiling point:
92-93 °C360 mm Hg(lit.)
alpha 
34 º (589nm, c=1, MeOH)
Density 
1.183 g/mL at 25 °C(lit.)
vapor density 
3.2 (vs air)
vapor pressure 
13.8 mm Hg ( 21.1 °C)
refractive index 
n20/D 1.438(lit.)
Flash point:
93 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform, Methanol (Slightly)
form 
Liquid
color 
Clear colorless to very pale yellow
optical activity
[α]20/D +35°, c = 1 in methanol
explosive limit
21%
Water Solubility 
insoluble
BRN 
1420784
Dielectric constant
22.9(20℃)
CAS DataBase Reference
67843-74-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T
Risk Statements 
45-10-23/24/25-34-43
Safety Statements 
53-45
RIDADR 
UN 2023 6.1/PG 2
WGK Germany 
3
RTECS 
TX4900000
Autoignition Temperature
1421 °F
HazardClass 
6.1
PackingGroup 
II
HS Code 
29038900

MSDS

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(S)-(+)-Epichlorohydrin Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Chemical Properties

Epichlorhydrin is a colourless liquid with odour, b.p. 115°C.

Uses

(S)-(+)-Epichlorohydrin is utilized for the synthesis of macquarimicins and hydroxyisoxazolidines and (+)-cis-sylvaticin, which is a potential antitumor agent. It is used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators. It acts as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels, lacquers and cement for celluloid. It is also used as a stabilizer and also useful as a bifunctional alkylating agent with the potential to form DNA cross-links.

Uses

S-enantiomer of Epichlorohydrin, (S)-Epichlorohydrin), an important industrial chemical, is a bifunctional alkylating agent with the potential to form DNA cross-links. It is used as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels and lacquers, cement for Celluloid. Also, it is used as stabilizer.

Definition

ChEBI: (S)-epichlorohydrin is an epichlorohydrin. It is functionally related to a (R)-1,2-epoxypropane. It is an enantiomer of a (R)-epichlorohydrin.

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