2,5-Dichloronitrobenzene Chemical Properties

Melting point:

52-54 °C(lit.)

Boiling point:

267 °C

Density 

1,442 g/cm³

vapor density 

6.6 (vs air)

vapor pressure 

<0.1 mm Hg ( 25 °C)

refractive index 

1.4390 (estimate)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

0.083g/l

color 

Pale Yellow

explosive limit

2.4-8.5%(V)

Water Solubility 

Soluble in water, ethanol, ether, benzene, carbon disulfide. Slightly soluble in carbon tetrachloride.

BRN 

778109

LogP

2.87 at 25℃

CAS DataBase Reference

89-61-2(CAS DataBase Reference)

IARC

2B (Vol. 65, 123) 2020

NIST Chemistry Reference

Benzene, 1,4-dichloro-2-nitro-(89-61-2)

EPA Substance Registry System

2,5-Dichloronitrobenzene (89-61-2)

Safety Information

Hazard Codes 

Xn,N

Risk Statements 

22-36-51/53

Safety Statements 

26-60

RIDADR 

UN 3077 9/PG 3

WGK Germany 

2

RTECS 

CZ5260000

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29049085

Hazardous Substances Data

89-61-2(Hazardous Substances Data)

MSDS

• Language:English Provider:Nitro-p-dichlorobenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,5-Dichloronitrobenzene Usage And Synthesis

Chemical Properties

yellow flakes

Uses

2,5-Dichloronitrobenzene is a reagent used in the synthesis of antitrypanosomal, antileishmanial and antimalarial agents. Also it is used in the synthesis of lysophosphatidic acid acyltransferase-β inhibitors.

Production Methods

Nitration of 1,4-dichlorobenzene with mixed acid at 35 – 65 ℃ results in a 98 % yield of essentially pure 2,5-Dichloronitrobenzene.

Purification Methods

Crystallise the nitrobenzene from absolute EtOH. [Beilstein 5 IV 726.]

2,5-Dichloronitrobenzene(89-61-2)Related Product Information

• 1,2-Dichlorobenzene
• 3-Nitrobenzaldehyde
• Sodium 3-nitrobenzenesulphonate
• 4-Nitrobenzoic acid
• 3,4-Difluoronitrobenzene
• 1,4-Dichlorobenzene
• 1,3-Dinitrobenzene
• 2,5-Dichloronitrobenzene
• NITROGEN DIOXIDE
• p-Dichlorobenzene
• Quintozine
• 2,5-Dichloro-3-nitrobenzoic acid
• 1,2,4-Trichloro-5-nitrobenzene
• 2,6-Dichloronitrobenzene
• 2,3-DICHLORONITROBENZENE,2,3-DICHLORONITROBENZENE 99%,2,3-DICHLORONITROBENZENE PESTANAL, 250 M
• TECNAZENE
• 1,2,3,4-TETRACHLORO-5,6-DINITROBENZENE
• 2,5-DICHLORO-4-NITROANILINE