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2,5-Dichloronitrobenzene

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2,5-Dichloronitrobenzene Basic information

Product Name:
2,5-Dichloronitrobenzene
Synonyms:
  • Benzene, 2,5-dichloronitro-
  • Benzene,1,4-dichloro-2-nitro-
  • Benzene,1-nitro-2,5-dichloro
  • NITRO-P-DICHLOROBENZENE
  • 2-NITRO-1,4-DICHLOROBENZENE
  • 2-NITRO-P-DICHLOROBENZENE
  • 2,5-DICHLORO-1-NITROBENZENE
  • 2,5-DICHLORONITROBENZENE
CAS:
89-61-2
MF:
C6H3Cl2NO2
MW:
192
EINECS:
201-923-3
Product Categories:
  • Aromatic Halides (substituted)
  • Benzene derivates
  • Intermediates of Dyes and Pigments
  • Dyestuff Intermediates
Mol File:
89-61-2.mol
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2,5-Dichloronitrobenzene Chemical Properties

Melting point:
52-54 °C(lit.)
Boiling point:
267 °C
Density 
1,442 g/cm3
vapor density 
6.6 (vs air)
vapor pressure 
<0.1 mm Hg ( 25 °C)
refractive index 
1.4390 (estimate)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
0.083g/l
color 
Pale Yellow
explosive limit
2.4-8.5%(V)
Water Solubility 
Soluble in water, ethanol, ether, benzene, carbon disulfide. Slightly soluble in carbon tetrachloride.
BRN 
778109
LogP
2.87 at 25℃
CAS DataBase Reference
89-61-2(CAS DataBase Reference)
IARC
2B (Vol. 65, 123) 2020
NIST Chemistry Reference
Benzene, 1,4-dichloro-2-nitro-(89-61-2)
EPA Substance Registry System
2,5-Dichloronitrobenzene (89-61-2)
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
22-36-51/53
Safety Statements 
26-60
RIDADR 
UN 3077 9/PG 3
WGK Germany 
2
RTECS 
CZ5260000
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29049085
Hazardous Substances Data
89-61-2(Hazardous Substances Data)

MSDS

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2,5-Dichloronitrobenzene Usage And Synthesis

Chemical Properties

yellow flakes

Uses

2,5-Dichloronitrobenzene is a reagent used in the synthesis of antitrypanosomal, antileishmanial and antimalarial agents. Also it is used in the synthesis of lysophosphatidic acid acyltransferase-β inhibitors.

Uses

2,5-Dichloronitrobenzene is a reagent used in the synthesis of antitrypanosomal, antileishmanial and antimalarial agents. Also it is used in the synthesis of lysophosphatidic acid acyltransferase-β in hibitors.

Production Methods

Nitration of 1,4-dichlorobenzene with mixed acid at 35 – 65 ℃ results in a 98 % yield of essentially pure 2,5-Dichloronitrobenzene.

Purification Methods

Crystallise the nitrobenzene from absolute EtOH. [Beilstein 5 IV 726.]

2,5-Dichloronitrobenzene Preparation Products And Raw materials

Preparation Products

Raw materials

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