1,2,4,5-Tetrachlorobenzene Chemical Properties

Melting point:

139 °C

Boiling point:

240-246 °C(lit.)

Density 

1.858

vapor pressure 

5 at 25 °C (extrapolated, Mackay et al., 1982)

refractive index 

1.5348 (estimate)

Flash point:

>230 °F

storage temp. 

0-6°C

solubility 

0.0003g/l

form 

Crystalline Solid

color 

Light pink to gray

Water Solubility 

insoluble. <0.1 g/100 mL at 21 ºC

BRN 

1618315

Henry's Law Constant

0.10 at 20 °C (gas stripping-GC, Oliver, 1985)

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents. Reacts explosively with alkaline methanol solutions.

CAS DataBase Reference

95-94-3(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1,2,4,5-tetrachloro-(95-94-3)

EPA Substance Registry System

1,2,4,5-Tetrachlorobenzene (95-94-3)

Safety Information

Hazard Codes 

Xn,T,F,N

Risk Statements 

22-36/37/38-23/24/25-11-36-20/21/22-51/53

Safety Statements 

26-36-45-27-16-36/37-61

RIDADR 

UN 3077 9/PG 3

WGK Germany 

3

RTECS 

DB9450000

TSCA 

Yes

HazardClass 

9

HS Code 

29036990

Hazardous Substances Data

95-94-3(Hazardous Substances Data)

Toxicity

Acute oral LD50 for rats 1,500 mg/kg, mice 1,035 mg/kg (quoted, RTECS, 1985).

MSDS

• Language:English Provider:1,2,4,5-Tetrachlorobenzene
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1,2,4,5-Tetrachlorobenzene Usage And Synthesis

Chemical Properties

white solid

Uses

Intermediate for herbicides and defoliants, insecticide, impregnant for moisture resistance, electrical insulation.

Uses

1,2,4,5-Tetrachlorobenzene was used to study the environmental behavior of hexachlorobutadiene (HCBD).

Definition

ChEBI: A tetrachlorobenzene carrying chloro groups at positions 1, 2, 4 and 5.

Environmental Fate

Biological. A mixed culture of soil bacteria or a Pseudomonas sp. transformed 1,2,4,5- tetrachlorobenzene to 2,3,5,6-tetrachlorophenol (Ballschiter and Scholz, 1980). After incubation in sewage sludge for 32 d under anaerobic conditions, 1,2,4,5-tetrachlorobenzene did not biodegrade (Kirk et al., 1989).
In an enrichment culture derived from a contaminated site in Bayou d’Inde, LA, 1,2,4,5- tetrachlorobenzene underwent reductive dechlorination to 1,2,4-trichlorobenzene. The maximum dechlorination rate, based on the recommended Michaelis-Menten model, was 5.5 nM/d (Pavlostathis and Prytula, 2000).
Photolytic. Irradiation (λ ≥285 nm) of 1,2,4,5-tetrachlorobenzene (1.1–1.2 mM/L) in an acetonitrile-water mixture containing acetone (0.553 mM) as a sensitizer gave the following products (% yield): 1,2,4-trichlorobenzene (25.3), 1,3-dichlorobenzene (8.1), 1,4-dichlorobenzene (3.6), 2,2′,3,4′,5,5′,6-heptachlorobiphenyl (4.19), four hexachlorobiphenyls (6.78), four pentachlorobiphenyls (2.33), one tetrachlorobiphenyl (0.32), 2,4,5-trichloroacetophenone, and (2,4,5- trichlorophenyl)acetonitrile (Choudhry and Hutzinger, 1984). Without acetone, the identified photolysis products (% yield) included 1,2,4-trichlorobenzene (27.7), 1,3-dichlorobenzene (0.3), 1,4-dichlorobenzene (8.5), pentachlorobenzene (trace), 1,2,3,4-tetrachlorobenzene (0.45), 1,2,3,5- tetrachlorobenzene (1.11), 2,2′,3,4′,5,5′,6-heptahlorobiphenyl (1.24), three hexachlorobiphenyls (1.19), and four pentachlorobiphenyls (0.56) (Choudhry and Hutzinger, 1984). The sunlight irradiation of 1,2,4,5-tetrachlorobenzene (20 g) in a 100-mL borosilicate glass-stoppered Erlenmeyer flask for 28 d yielded 26 ppm heptachlorobiphenyl (Uyeta et al., 1976).
Chemical/Physical. Based on an assumed base-mediated 1% disappearance after 16 d at 85 °C and pH 9.70 (pH 11.26 at °C), the hydrolysis half-life was estimated to be >900 yr (Ellington et al., 1988).

Purification Methods

Crystallise it from EtOH, ether, *benzene, *benzene/EtOH or carbon disulfide. [Beilstein 5 IV 668.]

1,2,4,5-Tetrachlorobenzene (95-94-3)Related Product Information

• 1,3-Dichlorobenzene
• Chlorphenamine maleate
• 2-Chlorobenzaldehyde
• 2,4-Dichlorobenzyl chloride
• HexanitrodiphenylaMine
• 1,2-Dichlorobenzene
• 1,2,4-Trichlorobenzene
• 1,2,4,6-tetrachlorobenzen
• Chlorthal
• Quintozine
• 2,3,5,6-TETRACHLOROTHIOANISOLE
• PENTACHLOROBENZENE
• 2,3,5,6-Tetrachloroterephthaloyl chloride
• p-Dichlorobenzene
• TECNAZENE
• Pentachlorophenol
• PENTACHLOROTHIOANISOLE
• Pentachloroaniline