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Sodium picosulfate

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Sodium picosulfate Basic information

Product Name:
Sodium picosulfate
Synonyms:
  • 4,4'-(2-Pyridinylmethylene)bis(phenol)bis(sulfuric acid sodium) salt
  • 4 4'-(2-PYRIDINYLMETHYLENE) BISPHENOL BI S(HYDROGEN SULFATE )(ESTER) DISODIUM SALT
  • Sodium Picosulfate n -Hydrate
  • DA 1773
  • DA-1773
  • LA 391
  • C13072
  • Sodium Picosulfate (50 mg)
CAS:
10040-45-6
MF:
C18H13NO8S2.2Na
MW:
481.41
EINECS:
233-120-9
Product Categories:
  • API
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Inhibitors
  • 10040-45-6
Mol File:
10040-45-6.mol
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Sodium picosulfate Chemical Properties

Melting point:
283-286°C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Freely soluble in water, slightly soluble in ethanol 96 per cent.
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChI
InChI=1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2
InChIKey
GOZDTZWAMGHLDY-UHFFFAOYSA-L
SMILES
C(C1N=CC=CC=1)(C1=CC=C(OS([O-])(=O)=O)C=C1)C1C=CC(OS([O-])(=O)=O)=CC=1.[Na+].[Na+]
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Safety Information

HS Code 
2933399090
Toxicity
mouse,LD50,intraperitoneal,2900mg/kg (2900mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATIONBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977.
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Sodium picosulfate Usage And Synthesis

Chemical Properties

Off-White Solid

Originator

Guttalax, De Angelini, Italy ,1967

Uses

Sodium picosulfate acts as a stimulant laxative by increasing the frequency and the force of peristalsis and promoting electrolyte and water retention in the colon. Sodium picosulfate is most often used as laxatives.

Uses

Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria.

Definition

ChEBI: Sodium picosulfate is an aryl sulfate and a member of pyridines.

Therapeutic Function

Laxative

Side effects

Major minor side effects for Sodium Picosulfate:Diarrhoea, Abdominal pain, Nausea and vomiting, and Stomach cramps.

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