2,5,8,11,14-pentaoxahexadecan-16-oic acid Chemical Properties

Boiling point:

379.6±32.0 °C(Predicted)

Density 

1.125±0.06 g/cm3(Predicted)

storage temp. 

Storage temp. 2-8°C

solubility 

DMSO : 100 mg/mL (375.53 mM; Need ultrasonic)

pka

3.39±0.10(Predicted)

form 

Liquid

color 

Colorless to light yellow

2,5,8,11,14-pentaoxahexadecan-16-oic acid Usage And Synthesis

Description

m-PEG5-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

IC 50

PEGs

References

[1] TaoDeng, et al. Monodisperse oligoethylene glycols modified Propofol prodrugs. Bioorganic & Medicinal Chemistry Letters.

2,5,8,11,14-pentaoxahexadecan-16-oic acid (16024-66-1)Related Product Information

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