rosoxacin Chemical Properties

Melting point:

290°

Boiling point:

500.8±50.0 °C(Predicted)

Density 

1.317±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMF (Very Slightly)

form 

Solid

pka

6.48±0.41(Predicted)

color 

Light Beige to Beige

rosoxacin Usage And Synthesis

Uses

Antibacterial.

Definition

ChEBI: A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid that is substituted by an ethyl group at position 1 and by a pyridin-4-yl group at position 7. An antibacterial drug, active against Neisseria gonorrhoeae, it has be n used for treating urinary tract infections and certain sexually transmitted diseases.

brand name

Roxadyl (Sterling Winthrop).

Pharmacokinetics

A single oral dose of 300 mg produces a mean peak plasma concentration of 4–5 mg/L at about 2–4 h, with an apparent elimination half-life of about 6 h. Elimination in the urine is partly as the N-oxide metabolite and the glucuronide of this metabolite.
Side effects are those common to quinolones, notably gastrointestinal tract and CNS disturbances. About 50% of patients treated with single oral doses of 100–400 mg developed dizziness, drowsiness, altered visual perception and other CNS effects.
It is effective as single-dose treatment of patients with urethral and anorectal gonorrhea, but coexistent C. trachomatis infection is not eliminated from most patients and postgonococcal urethritis develops in up to 30%.

rosoxacin(40034-42-2)Related Product Information

• 2-AMINO-4-METHYLBENZALDEHYDE
• 3-P-TOLYL-PROPAN-1-OL
• 1-METHYL-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID
• 3-(4-METHYLPHENYL)PROPIONIC ACID
• 2-Methyl-3-(4-methylphenyl)prop-1-ene
• 3-(N-Phenyl-N-methyl)aminoacrolein
• 3-(4-METHYLPHENYL)PROPIONALDEHYDE
• 3-DIMETHYLAMINO-2-METHYL-2-PROPENAL
• 4-(4-Pyridinyl)benzaldehyde
• 2-Benzylacrylic acid
• rosoxacin
• 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
• 4-Phenylpyridine
• 3-PYRIDIN-4-YLANILINE