1-butylbiguanide Chemical Properties

Melting point:

174-176 °C

Boiling point:

271.89°C (rough estimate)

Density 

1.0291 (rough estimate)

refractive index 

1.8070 (estimate)

pka

12.27±0.10(Predicted)

1-butylbiguanide Usage And Synthesis

Uses

Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase

Definition

ChEBI: Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide.

brand name

Adebit;Andebit;Andelit;Andere;Biforon;Bigunal;Biquinal;Bs-5892;Bufonamin;Bulbonin;Diabrin;Dutformin;Gliporal;Insulamin;Krebon;Panformin;Silubin retard;Sindiatil;Tidemol retard;Ziavetine.

World Health Organization (WHO)

Buformin is an analogue of phenformin. See WHO comment for phenformin. (Reference: (WHODI) WHO Drug Information, 2, 4, 1977)

1-butylbiguanide(692-13-7)Related Product Information

• Chlorhexidine Diacetate
• ALEXIDINE DIHYDROCHLORIDE
• Chlorhexidine digluconate
• Chlorhexidine
• Chlorhexidine hydrochloride
• BuforMin Hydrochloride
• 1-butylbiguanide
• Chlorhexidine diacetate
• Poly(hexamethylenebiguanide)
• Etoformin
• N-((p-Chlorophenyl)amidino)-4-methyl-1-piperidinecarboxamidine monohyd rochloride
• 4,6-DIPYRROLIDIN-1-YL-1,3,5-TRIAZIN-2(1H)-ONE HYDRAZONE
• 1-cyclohexylbiguanide monohydrochloride
• BPC 151
• chlorhexidine phosphanilate
• N-((p-Chlorophenyl)amidino)-1-piperidinecarboxamidine hydrochloride
• CHLORHEXIDINE-RING-UL-14C DIHYDROCHLORIDE
• CHLORHEXIDINE-RING-UL-14C DIGLUCONATE