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Peramivir

Basic information Safety Supplier Related

Peramivir Basic information

Product Name:
Peramivir
Synonyms:
  • (1S,2S,3R,4R)-3-(1-acetaMido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid
  • 3(R)-[1(S)-AcetaMido-2-ethylbutyl]-4(R)-guanidino-2(S)- hydroxycyclopentane-1(S)-carboxylic acid
  • PERAMIVIRUM
  • (1S,2S,3S,4R)-3-[(1S)-1-AcetaMido-2-ethylbutyl]-4-[(diaMinoMethylene)aMino]-2-hydroxycyclopentanecarboxylic acid
  • (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid
  • (1R,2R,3S,4S)-3-((R)-1-acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentane-1-carboxylic acid
  • Peramivir USP/EP/BP
  • Peramivirr
CAS:
229614-55-5
MF:
C15H28N4O4
MW:
328.41
EINECS:
1308068-626-2
Product Categories:
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
  • API
  • 229614-55-5
Mol File:
229614-55-5.mol
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Peramivir Chemical Properties

InChI
InChI=1/C15H28N4O4/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19)/t9-,10+,11+,12-,13+/s3
InChIKey
XRQDFNLINLXZLB-YSVRZGPENA-N
SMILES
[C@@]1([H])([C@H](C(CC)CC)NC(C)=O)[C@H](NC(N)=N)C[C@H](C(O)=O)[C@H]1O |&1:0,2,12,18,22,r|
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Peramivir Usage And Synthesis

Uses

Peramivir is a new antiviral agent for influenza treatment; it can be used as neuraminidase inhibitor for treating human and avian influenza

Definition

ChEBI: Peramivir is a member of the class of guanidines that is used (as its trihydrate) for the treatment of acute uncomplicated influenza in patients 18 years and older who have been symptomatic for no more than two days. It has a role as an antiviral drug and an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor. It is a member of cyclopentanols, a member of acetamides, a member of guanidines and a 3-hydroxy monocarboxylic acid. It contains a peramivir hydrate.

Pharmaceutical Applications

An intravenously administered neuraminidase inhibitor currently under investigation for the treatment of influenza infections in normal and high-risk patient populations. No drug interactions of note have yet been identified.

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