Methyl 2-bromomethyl-3-nitrobenzoate Chemical Properties

Melting point:

72-74°

Boiling point:

370.9±32.0 °C(Predicted)

Density 

1.624±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

soluble in Methanol

form 

Solid

color 

White to Light yellow

InChI

InChI=1S/C9H8BrNO4/c1-15-9(12)6-3-2-4-8(11(13)14)7(6)5-10/h2-4H,5H2,1H3

InChIKey

FCGIVHSBEKGQMZ-UHFFFAOYSA-N

SMILES

C(OC)(=O)C1=CC=CC([N+]([O-])=O)=C1CBr

Safety Information

RIDADR 

UN 3261 8/PG III

HazardClass 

IRRITANT

HazardClass 

8

PackingGroup 

III

HS Code 

2916310090

Methyl 2-bromomethyl-3-nitrobenzoate Usage And Synthesis

Description

Methyl 2-bromomethyl-3-nitrobenzoate is a white or light yellow solid under normal temperature and pressure. It is insoluble in water but soluble in alcoholic organic solvents. It is an organic ester derivative that can be used as an organic synthesis intermediate and a raw material for pharmaceutical chemical synthesis. It is a crucial synthesis intermediate for the drug molecule lenalidomide. Lenalidomide is an antineoplastic drug. The ester group and benzyl bromide unit in the Methyl 2-bromomethyl-3-nitrobenzoate structure are easily convertible functional groups. Its structure contains a strong electron-attracting nitro group and an easily leaving bromine atom. The nitro group is a strong electron-withdrawing group that can increase the reactivity of molecules through conjugation effects and electron attraction. Due to these properties, it has wide applications in organic synthesis transformations. 

Chemical Properties

Pale Yellow Solid

Methyl 2-bromomethyl-3-nitrobenzoate(98475-07-1)Related Product Information

• Methylparaben
• Methyl 3-(bromomethyl)benzoate
• Methyl 2-methyl-3-nitrobenzoate
• Methyl 4-(bromomethyl)benzoate
• Methyl acrylate
• Bromotrimethylsilane
• Paraquat dichloride
• Methyl acetate
• Methanol
• Methyl 4-methylbenzoate
• Basic Violet 1
• Methyl 2-bromobenzoate
• Acetonitrile
• Kresoxim-methyl
• Methyl 2-bromopropionate
• Methyl 2-bromohexanoate
• Methyl
• METHYL 2-BROMOMETHYL-5-FLUORO-BENZOATE