Basic information Safety Supplier Related

Lipstatin

Basic information Safety Supplier Related

Lipstatin Basic information

Product Name:
Lipstatin
Synonyms:
  • N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl ester
  • (-)-Lipstatin N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl ester
  • Orlistat Tetradehydro Impurity
  • Lipstatin
  • L-Leucine, N-formyl-,(1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-ylester
  • (2S-(2alpha(1R*,3Z,6Z),3beta))-N-Formyl-L-leucine 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)-3,6-dodecadienyl ester
  • Lipstatin Solution, 100ppm
  • [(2S,4E,7E)-1-(3-hexyl-4-oxooxetan-2-yl)trideca-4,7-dien-2-yl] (2S)-2-formamido-3-methylpentanoate
CAS:
96829-59-3
MF:
C29H49NO5
MW:
491.7
EINECS:
619-246-0
Product Categories:
  • Amino Acids & Derivatives
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
96829-59-3.mol
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Lipstatin Chemical Properties

Boiling point:
627.4±55.0 °C(Predicted)
Density 
0.993
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka
14.57±0.23(Predicted)
form 
Oil
color 
Clear Colorless to Light Yellow
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Lipstatin Usage And Synthesis

Uses

Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and/or prevention of obesity and related diseases.

Uses

Lipstatin is a potent irreversible inhibitor of pancreatic lipase, produced by Streptomyces toxytricini and first reported in 1987. In vivo, lipstatin acts to block the absorption of triglycerides while allowing fatty acid absorption. The tetrahydro analogue of lipstatin, orlistat, although less potent, was developed for the treatment of obesity.

LipstatinSupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Chembest Research Laboratories Limited
Tel
021-20908456
Email
sales@BioChemBest.com
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Email
sales@sunlidabio.com
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Lipstatin(96829-59-3)Related Product Information