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1,3-Dioxo-2-isoindolineaceticacid

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1,3-Dioxo-2-isoindolineaceticacid Basic information

Product Name:
1,3-Dioxo-2-isoindolineaceticacid
Synonyms:
  • N-(1,3-Dihydro-1,3-dioxoisobenzofuran-4-yl)acetamide
  • AcetaMide, N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-
  • 3-AcetylaMino-phthalsaeure-anhydrid
  • 3-AcetaMidophthalic anhydride
  • 1,3-Dioxo-2-isoindolineaceticacid CAS:6296-53-3
  • 3-AcetylaMinophthalic Anhydride
  • N-(1,3-Dioxo-1,3-dihydro-2-benzofuran-4-yl)acetaMide
  • NSC 16261
CAS:
6296-53-3
MF:
C10H7NO4
MW:
205.17
EINECS:
808-040-8
Mol File:
6296-53-3.mol
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1,3-Dioxo-2-isoindolineaceticacid Chemical Properties

Melting point:
185-186℃
Boiling point:
489.1±28.0 °C(Predicted)
Density 
1.512±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol
form 
Solid
pka
13.81±0.20(Predicted)
color 
Off-White to Pale Yellow
Stability:
Moisture Sensitive
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Safety Information

HS Code 
2924.29.7790
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1,3-Dioxo-2-isoindolineaceticacid Usage And Synthesis

Uses

3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Apremilast Impurity 2

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