Azidoacetic acid methyl ester Chemical Properties

Boiling point:

35 °C

Density 

1.182 g/mL at 25 °C

refractive index 

n20/D1.440

Flash point:

48℃

Safety Information

Hazard Codes 

Xi

Risk Statements 

5-10-36/37/38

Safety Statements 

26

RIDADR 

UN 1993C 3 / PGIII

WGK Germany 

3

Azidoacetic acid methyl ester Usage And Synthesis

Uses

• Methyl 2-azidoacetate is widely used as a precursor to build triazole derivatives via alkyne-azide click chemistry. Some of the examples include the synthesis of coumarin-triazole derivatives as potential antiplasmodial agents and macrocyclic triazole containing largazole analogs as histone deacetylases-1 (HDAC1) inhibitors.
• It can be used to synthesize various pyrrole derivatives by Knoevenagel condensation as in the synthesis of near-infrared boron dipyrromethene (BODIPY) donors for organic tandem solar cells.
• It can also be used in Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles.
• Synthesis of highly fluorescent pyreno[2,1-b]pyrroles using methyl 2-azidoacetate as one of the reagents.

Azidoacetic acid methyl ester(1816-92-8)Related Product Information

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• Azidoacetic acid methyl ester