p-Hydroxybenzoic acid ethyl ester sodium salt Chemical Properties

Melting point:

>115°C(free ester)

Density 

1.34[at 20℃]

Flash point:

121°C

storage temp. 

Store at +15°C to +25°C.

solubility 

White or almost white, hygroscopic, crystalline powder.

pka

8.4[at 20 ℃]

form 

Solid

color 

White to Off-White

PH

10 (1g/l, H2O, 20°C)

Water Solubility 

1000g/L at 23℃

Boiling point:

297°C (1013 hPa)(free ester),(decomposition)

LogP

-0.14 at 23℃

CAS DataBase Reference

35285-68-8(CAS DataBase Reference)

Safety Information

WGK Germany 

WGK 1 slightly water endangering

HS Code 

2918 29 00

Toxicity

LD50 orally in Rabbit: > 2000 mg/kg

p-Hydroxybenzoic acid ethyl ester sodium salt Usage And Synthesis

Chemical Properties

White or almost white, hygroscopic, crystalline powder.

Uses

Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard ethyl 4-hydroxybenzoate.

Flammability and Explosibility

Non flammable

Contact allergens

This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.

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• p-Hydroxybenzoic acid ethyl ester sodium salt