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2,3,5-Trichloropyridine

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2,3,5-Trichloropyridine Basic information

Product Name:
2,3,5-Trichloropyridine
Synonyms:
  • 2,3,5-trichloro-pyridin
  • Trichloropyridine,98%
  • 2,3,5-TRICHLOROPYRIDINE 98+%
  • 2,3,5-TRICHLOROPYRIDINE
  • 3,5,6-Trichloropyridine
  • 5-Trichloropyridine
  • Pyridine, 2,3,5-trichloro-
  • 2,3,5 - cross-linked with pyridine
CAS:
16063-70-0
MF:
C5H2Cl3N
MW:
182.44
EINECS:
407-270-2
Product Categories:
  • alkyl chloride
  • Building Blocks
  • C5
  • C5 to C6
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Pyridine
  • Chloropyridines
  • Halopyridines
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Chlorinated heterocyclic series
  • Heterocyclic Building Blocks
  • Pyridines
  • bc0001
Mol File:
16063-70-0.mol
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2,3,5-Trichloropyridine Chemical Properties

Melting point:
46-50 °C (lit.)
Boiling point:
219 °C (lit.)
Density 
1.539±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-2.92±0.10(Predicted)
form 
Solid
color 
Off-white to pale yellow
Water Solubility 
Slightly soluble in water.
BRN 
119384
CAS DataBase Reference
16063-70-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
52/53-36/37/38
Safety Statements 
61-37/39-26
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
2
RTECS 
UU0525000
Hazard Note 
Irritant
HS Code 
29333990
Toxicity
mouse,LD50,intraperitoneal,430mg/kg (430mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)LIVER: FATTY LIVER DEGERATIONBEHAVIORAL: ANTIPSYCHOTIC,Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967.

MSDS

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2,3,5-Trichloropyridine Usage And Synthesis

Chemical Properties

Beige powder

Uses

2,3,5-Trichloropyridine may be used in the synthesis of 3,5-dichloro-2-arylpyridines via palladium acetate-catalyzed ligand-free Suzuki reaction with arylboronic acids.

General Description

Separation and migration behavior of 2,3,5-trichloropyridine has been studied by micellar electrokinetic chromatography. Crystal structure of 2,3,5-trichloropyridine has been reported. Mol-ecules of 2,3,5-trichloropyridine in crystal are stacked along the short a axis and forms a layer structure. 2,3,5-Trichloropyridine is reported to undergo nucleophilic displacement reaction in ionic liquid to afford the corresponding 2-aryloxylpropionate.

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