MT-4
MT-4 Basic information
- Product Name:
- MT-4
- Synonyms:
-
- MT-4
- Benzeneacetamide, N-[4-[[4-(dimethylamino)-6-methyl-2-pyrimidinyl]amino]phenyl]-
- MT-4, 10 mM in DMSO
- MT-4 Cells Line
- CAS:
- 2327925-35-7
- MF:
- C21H23N5O
- MW:
- 361.44
- Mol File:
- 2327925-35-7.mol
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MT-4 Chemical Properties
- Density
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 14.54±0.70(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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MT-4 Usage And Synthesis
Uses
MT-4 is a derivative of a tissue transglutaminase (TG2) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel.
References
[1] Sima LE, et al. Small Molecules Target the Interaction between Tissue Transglutaminase and Fibronectin. Mol Cancer Ther. 2019 Jun;18(6):1057-1068. DOI:10.1158/1535-7163.MCT-18-1148
MT-4Supplier
Yingkou Tianyuan Chemical Research Institute Co., Ltd.
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- 086-17722431616-6 17722431616
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Henan Alfachem Co.,Ltd.
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- 0371-55051623 18137891487
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TargetMol Chemicals Inc.
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- +1-781-999-5354; +17819995354
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Shenzhen Hongyuan Import and Export Trade Co., Ltd.
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- 15013245021
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Shanghai Kanglang Biotechnology Co., Ltd.
- Tel
- 021-61998208 18217752821
- sales@klbio.cn