Basic information Safety Supplier Related

N-LAUROYL-D-ERYTHRO-SPHINGOSINE

Basic information Safety Supplier Related

N-LAUROYL-D-ERYTHRO-SPHINGOSINE Basic information

Product Name:
N-LAUROYL-D-ERYTHRO-SPHINGOSINE
Synonyms:
  • N-LAUROYL-D-ERYTHRO-SPHINGOSINE
  • N-LAUROYL-D-SPHINGOSINE
  • C12 CERAMIDE
  • C12-D-ERYTHRO-SPHINGOSINE
  • CERAMIDE C12
  • N-lauroylsphingosine
  • N-LAUROYL-D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL
  • N-Lauroyl-D-erythro-sphingosineCeramide C12
CAS:
74713-60-3
MF:
C30H59NO3
MW:
481.79
Product Categories:
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
74713-60-3.mol
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N-LAUROYL-D-ERYTHRO-SPHINGOSINE Chemical Properties

Melting point:
70 - 72°C
Boiling point:
579.38°C (rough estimate)
Density 
0.9777 (rough estimate)
refractive index 
1.6310 (estimate)
storage temp. 
-20°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
pka
13.54±0.20(Predicted)
form 
Solid
color 
White to Off-White
BRN 
1717021
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Safety Information

Safety Statements 
24/25
WGK Germany 
3

MSDS

  • Language:English Provider:ACROS
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N-LAUROYL-D-ERYTHRO-SPHINGOSINE Usage And Synthesis

Chemical Properties

white powder

Uses

C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used:

  • as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
  • as an internal standard for lipid extraction in U87MG (human glioma cell line)
  • as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues

Uses

Ceramide is one of the simplest sphingolipids, consisting of a sphingosine base N-linked to a fatty acid, and is a membrane mediator for cell-signaling events. N-Acyl chain length of membrane ceramides can influence bidimensional transitions, condensed domain morphology, and interfacial thickness.

Definition

ChEBI: N-dodecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as dodecanoyl (lauroyl). It is functionally related to a dodecanoic acid.

General Description

Ceramide is a sphingolipid with long acyl chain attached to a fatty. It is synthesized in the endoplasmic reticulum by ceramide synthase.

Biochem/physiol Actions

Ceramides?are signaling sphingolipids, which are implicated in regulating stress responses and inflammation. It also regulates cell growth arrest, differentiation and apoptosis.

N-LAUROYL-D-ERYTHRO-SPHINGOSINESupplier

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