ChemicalBook > Product Catalog > API > Hormones and the Endocrine System > Adrenal corticosteroids > Hydrocortisone
Hydrocortisone
Hydrocortisone Basic information
- Product Name:
- Hydrocortisone
- Synonyms:
-
- hydrocortisone aceponate
- [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
- [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
- propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester
- Hydrocortisone 17-Propionate 21-Acetate
- Hydrocortisonepropylacetate
- Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-17-(1-oxopropoxy)-, (11β)-
- Efficort
- CAS:
- 74050-20-7
- MF:
- C26H36O7
- MW:
- 460.56
- Product Categories:
-
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
- API
- Mol File:
- 74050-20-7.mol
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Hydrocortisone Chemical Properties
- Melting point:
- 144-146°C
- Density
- 1.23±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Pale Beige
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Hydrocortisone Usage And Synthesis
Description
Hydrocortisone aceponate is the 17-a-propionate derivative of hydrocortisone-21-acetate. Its is reportedly significantly superior to the latter in the treatment of dermatoses of varying severity.
Chemical Properties
White to Off-White Solid
Originator
Beiersdorf (W.Germany)
Uses
A new topical hydrocortisone derivative with esterification in positions 17 and 21, inhibit the incorporation of [3H]thymidine in DNA in human skin fibroblasts less strongly than the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. Glucocorticosteroid.
Definition
ChEBI: Hydrocortisone aceponate is a corticosteroid hormone.
brand name
Retef
HydrocortisoneSupplier
Hangzhou Kehui Pharmaceutical Co.,Ltd Gold
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- 057187359773 18094707759
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J & K SCIENTIFIC LTD.
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Chemsky（shanghai）International Co.,Ltd.
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Suzhou ChemWe Chemical Co., Ltd.
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- 512-62706911 13401923197
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Hefei NaNo Biological Technology Co., Ltd.
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- 0551-65629887 18010855303
- sales@hfnhsw.com