Lubeluzole Chemical Properties

Melting point:

65.8°

alpha 

D20 +4.38° (c = 1 in methanol)

storage temp. 

2-8°C

solubility 

H2O: soluble2mg/mL, clear (warmed)

form 

powder

color 

white to beige

Water Solubility 

H2O: 2mg/mL, clear (warmed)

InChI

1S/C22H25F2N3O2S/c1-26(22-25-20-4-2-3-5-21(20)30-22)15-8-10-27(11-9-15)13-16(28)14-29-17-6-7-18(23)19(24)12-17/h2-7,12,15-16,28H,8-11,13-14H2,1H3/t16-/m0/s1

InChIKey

OZFSWVOEXHGDES-INIZCTEOSA-N

SMILES

Fc1c(ccc(c1)OC[C@@H](O)CN2CCC(CC2)N(C)c3[s]c4c(n3)cccc4)F

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

WGK Germany 

3

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Aquatic Chronic 4

Lubeluzole Usage And Synthesis

Definition

ChEBI: Lubeluzole is a member of benzothiazoles.

Biological Activity

Lubeluzole is an NMDA antagonist. Lubeluzole blocks glutamate release, as well as sodium and calcium gated ion channels. Lubeluzole displays neuroprotective properties in ischemia models.

Lubeluzole(144665-07-6)Related Product Information

• Sabeluzole
• 3-(4-fluorophenoxy)propan-1-amine
• Lubeluzole
• [3-(4-FLUOROPHENOXY)PROPYL]METHYLAMINE
• 4-AMINO-1-PIPERIDINE-ETHANOL
• 3-(3-fluorophenoxy)propan-1-amine