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N-Benzyl-N-methylethanolamine

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N-Benzyl-N-methylethanolamine Basic information

Product Name:
N-Benzyl-N-methylethanolamine
Synonyms:
  • 2-[methyl(phenylmethyl)amino]-ethano
  • Ethanol, 2-(benzylmethylamino)-
  • N-Benzyl-N-methylethanolamine,99%
  • N-Benzyl-N-Methyl
  • 2-[benzyl(Methyl)aMino]ethan-1-ol
  • 2-[BENZYL(METHYL)AMINO]ACETALDEHYDE
  • Ethanol, 2-[methyl(phenylmethyl)amino]-
  • N-Benzyl-N-methyl-2-aminoethanol
CAS:
101-98-4
MF:
C10H15NO
MW:
165.23
EINECS:
202-994-3
Product Categories:
  • Hydroxyethylamines
  • Aromatic alcohols and diols
Mol File:
101-98-4.mol
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N-Benzyl-N-methylethanolamine Chemical Properties

Boiling point:
95-105 °C2 mm Hg(lit.)
Density 
1.017 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.529(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
14.75±0.10(Predicted)
form 
Oil
color 
Colourless
BRN 
366412
CAS DataBase Reference
101-98-4(CAS DataBase Reference)
NIST Chemistry Reference
Ethanol, 2-[methyl(phenylmethyl)amino]-(101-98-4)
EPA Substance Registry System
Ethanol, 2-[methyl(phenylmethyl)amino]- (101-98-4)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-24/25
WGK Germany 
3
HS Code 
29214990

MSDS

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N-Benzyl-N-methylethanolamine Usage And Synthesis

Description

N-Benzyl-N-methylethanolamine is a surfactant that has a high capacity for adsorbing proteins. It is used as an efficient method to remove impurities from human immunoglobulin preparations and as an adsorbent in chromatographic methods. N-Benzyl-N-methylethanolamine has also been used as a diagnostic agent for the detection of chromatographically separated monoclonal antibodies, which are produced by activated B cells in culture. The antibody binds to the target protein and then the antibody-protein complex is isolated using a particle agglomeration technique. This method can be repeated multiple times and produce high concentrations of pure monoclonal antibodies.

Chemical Properties

clear yellowish liquid

Uses

2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.

General Description

N-Benzyl-N-methylethanolamine is a tertiary benzylamine. Electrochemical alkoxylation of N-benzyl-N-methylethanolamine is reported. Rate of proton exchange of N-benzyl-N-methylethanolamine in aqueous HCl has been reported.

N-Benzyl-N-methylethanolamine Preparation Products And Raw materials

Raw materials

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